Abrilumab
Abrilumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target integrin alpha-4.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
5 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ulcerative colitis | D003093 | EFO_0000729 | K51 | 2 | 2 | — | — | — | 4 |
| Crohn disease | D003424 | EFO_0000384 | K50 | 1 | 1 | — | — | — | 2 |
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | ABRILUMAB |
| INN | abrilumab |
| Description | Abrilumab (human mab) |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL3137351 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | Y9UQ37XT2T (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
ITGA4
ITGA4
Organism
Homo sapiens
Gene name
ITGA4
Gene synonyms
CD49D
NCBI Gene ID
Protein name
integrin alpha-4
Protein synonyms
269C wild type, alpha 4 subunit of VLA-4 receptor, antigen CD49D, alpha-4 subunit of VLA-4 receptor, CD49 antigen-like family member D, CD49d, Integrin alpha-IV, very late activation protein 4 receptor, alpha 4 subunit, VLA-4 subunit alpha
Uniprot ID
Mouse ortholog
Itga4 (16401)
integrin alpha-4 (Q00651)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 61 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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