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Acetohydroxamic acid
Lithostat (acetohydroxamic acid) is a small molecule pharmaceutical. Acetohydroxamic acid was first approved as Lithostat on 1983-05-31. It is used to treat urinary tract infections in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
urogenital diseasesD000091642
Trade Name
FDA
EMA
Lithostat
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Acetohydroxamic acid
Tradename
Company
Number
Date
Products
LITHOSTATMission PharmacalN-018749 RX1983-05-31
1 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
lithostatNew Drug Application2021-01-05
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
urinary tract infectionsEFO_0003103D014552N39.0
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
G: Genito urinary system and sex hormones
— G04: Urologicals
— G04B: Urologicals
— G04BX: Other urologicals in atc
— G04BX03: Acetohydroxamic acid
HCPCS
No data
Clinical
Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameACETOHYDROXAMIC ACID
INNacetohydroxamic acid
Description
Acetohydroxamic acid is a member of the class of acetohydroxamic acids that is acetamide in which one of the amino hydrogens has been replaced by a hydroxy group. It has a role as an EC 3.5.1.5 (urease) inhibitor and an algal metabolite. It is functionally related to an acetamide. It is a tautomer of a N-hydroxyacetimidic acid.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CC(=O)NO
Identifiers
PDB—
CAS-ID546-88-3
RxCUI16728
ChEMBL IDCHEMBL734
ChEBI ID27777
PubChem CID1990
DrugBankDB00551
UNII ID4RZ82L2GY5 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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5 adverse events reported
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