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Adriforant
Adriforant is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target histamine H3 receptor and histamine H4 receptor.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
6 clinical trials
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Mock data
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Atopic dermatitisD003876EFO_0000274L2033
PsoriasisD011565EFO_0000676L4011
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AsthmaD001249EFO_0000270J4511
Healthy volunteers/patients11
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameADRIFORANT
INNadriforant
Description
Adriforant is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target histamine H3 receptor and histamine H4 receptor.
Classification
Small molecule
Drug classhistamine H4 receptor antagonists
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CN[C@@H]1CCN(c2cc(NCC3CC3)nc(N)n2)C1
Identifiers
PDB
CAS-ID943057-12-3
RxCUI
ChEMBL IDCHEMBL1915540
ChEBI ID
PubChem CID
DrugBank
UNII IDD65H9YE9VU (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
HRH3
HRH3
HRH4
HRH4
Organism
Homo sapiens
Gene name
HRH3
Gene synonyms
GPCR97
NCBI Gene ID
Protein name
histamine H3 receptor
Protein synonyms
G protein-coupled receptor 97, G-protein coupled receptor 97, H3R
Uniprot ID
Mouse ortholog
Hrh3 (99296)
histamine H3 receptor (P58406)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 14 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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