Aglatimagene besadenovec
Aglatimagene besadenovec is a gene pharmaceutical. It is currently being investigated in clinical studies.
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
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Indications
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Agency Specific
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ATC Codes
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Clinical
Clinical Trials
402 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Prostatic neoplasms | D011471 | C61 | 16 | 37 | 17 | 3 | 185 | 250 | |
| Prostatic hyperplasia | D011470 | EFO_0000284 | N40 | 3 | 4 | 8 | 5 | 66 | 84 |
| Urinary retention | D016055 | HP_0000016 | R33 | — | — | — | 1 | 2 | 3 |
| Urinary bladder neck obstruction | D001748 | EFO_1000840 | N32.0 | — | — | — | 1 | 1 | 2 |
| Urinary tract infections | D014552 | EFO_0003103 | N39.0 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Lower urinary tract symptoms | D059411 | EFO_0008008 | 1 | 1 | 1 | — | 17 | 20 | |
| Adenocarcinoma | D000230 | 1 | 1 | 1 | — | 5 | 8 | ||
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | — | 2 | 1 | — | — | 3 |
| Drug therapy | D004358 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Glioma | D005910 | EFO_0000520 | 3 | 2 | — | — | — | 5 | |
| Urinary bladder neoplasms | D001749 | C67 | — | 1 | — | — | 3 | 4 | |
| Glioblastoma | D005909 | EFO_0000515 | 1 | 2 | — | — | — | 3 | |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | 1 | — | — | — | 2 |
| Astrocytoma | D001254 | EFO_0000271 | 1 | 1 | — | — | — | 2 | |
| Transitional cell carcinoma | D002295 | — | 1 | — | — | 1 | 2 | ||
| Neoplasms | D009369 | C80 | — | 1 | — | — | — | 1 | |
| Non-small-cell lung carcinoma | D002289 | — | 1 | — | — | — | 1 | ||
| Liver transplantation | D016031 | EFO_0010682 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 2 | — | — | — | 2 | 4 |
| Lung neoplasms | D008175 | C34.90 | 2 | — | — | — | — | 2 | |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 1 | — | — | — | — | 1 |
| Mesothelioma | D008654 | C45 | 1 | — | — | — | — | 1 | |
| Malignant pleural effusion | D016066 | J91.0 | 1 | — | — | — | — | 1 | |
| Ependymoma | D004806 | 1 | — | — | — | — | 1 | ||
| Uterine cervical neoplasms | D002583 | 1 | — | — | — | — | 1 | ||
| Colonic neoplasms | D003110 | C18 | 1 | — | — | — | — | 1 | |
| Kidney neoplasms | D007680 | EFO_0003865 | C64 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Prostatic diseases | D011469 | N42.9 | — | — | — | — | 7 | 7 | |
| Transurethral resection of prostate | D020728 | — | — | — | — | 4 | 4 | ||
| Urinary incontinence | D014549 | HP_0000020 | R32 | — | — | — | — | 3 | 3 |
| Pain | D010146 | EFO_0003843 | R52 | — | — | — | — | 2 | 2 |
| Prostatitis | D011472 | EFO_0003830 | N41 | — | — | — | — | 2 | 2 |
| Urologic neoplasms | D014571 | C64-C68 | — | — | — | — | 2 | 2 | |
| Infections | D007239 | EFO_0000544 | — | — | — | — | 2 | 2 | |
| Genetic predisposition to disease | D020022 | — | — | — | — | 2 | 2 | ||
| Therapeutic embolization | D004621 | — | — | — | — | 2 | 2 | ||
| Biopsy | D001706 | — | — | — | — | 2 | 2 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | AGLATIMAGENE BESADENOVEC |
| INN | aglatimagene besadenovec |
| Description | Aglatimagene besadenovec is a gene pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Gene |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL3544993 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 5Z72SSS34W (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Trends
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Additional graphs summarizing 12 documents
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Safety
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Adverse Events
Top Adverse Reactions
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12 adverse events reported
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