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Alseroxylon
Rautensin, Rauwiloid (alseroxylon) is a small molecule pharmaceutical. Alseroxylon was first approved as Rauwiloid on 1982-01-01.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Alseroxylon
Tradename
Company
Number
Date
Products
RAUWILOID3MN-008867 DISCN1982-01-01
1 products
RAUTENSINNovartisN-009215 DISCN1982-01-01
1 products
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Labels
FDA
EMA
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Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
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HCPCS
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Clinical
Clinical Trials
170 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
GoutD006073EFO_0004274M10211127436
HyperuricemiaD0334611744420
Chronic renal insufficiencyD051436N1833129
Heart failureD006333EFO_0003144I5015138
Cardiovascular diseasesD002318EFO_0000319I9841217
HypertensionD006973EFO_0000537I1013215
Kidney calculiD007669EFO_0004253N20.0123
Diabetic nephropathiesD003928EFO_00004011113
ManiaD000087122F30123
Left ventricular hypertrophyD017379EFO_000389633
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Precursor cell lymphoblastic leukemia-lymphomaD054198C91.024218
Non-hodgkin lymphomaD008228C85.92215
ObesityD009765EFO_0001073E66.9123
Type 2 diabetes mellitusD003924EFO_0001360E11123
PrehypertensionD058246212
Hiv infectionsD015658EFO_0000764B20112
NeoplasmsD009369C80112
Tumor lysis syndromeD015275E88.322
Coronary artery diseaseD003324I25.1112
Heart diseasesD006331EFO_0003777I51.91112
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
LeukemiaD007938C95268
Myelodysplastic syndromesD009190D462316
LymphomaD008223C85.9235
Multiple myelomaD009101C90.0134
Myeloid leukemia acuteD015470C92.0314
Obstructive sleep apneaD020181EFO_0003918G47.33123
Plasma cell neoplasmsD054219213
B-cell chronic lymphocytic leukemiaD015451C91.122
Burkitt lymphomaD002051C83.722
Metabolic syndromeD024821EFO_0000195E88.8122
Show 21 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients66
Heart disease risk factorsD00008274233
VasoconstrictionD01466122
Myeloproliferative disordersD009196D47.111
Graft vs host diseaseD006086D89.8111
VasodilationD01466411
TuberculosisD014376EFO_0000774A15-A1911
Inflammatory bowel diseasesD015212EFO_000376711
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Cutaneous leishmaniasisD016773B55.122
Prediabetic stateD011236EFO_1001121R73.0311
Insulin resistanceD007333EFO_000261411
Endoscopic retrograde cholangiopancreatographyD00276011
Iga glomerulonephritisD005922EFO_000419411
Fetal growth retardationD005317EFO_000049511
Non-alcoholic fatty liver diseaseD065626EFO_0003095K75.8111
Chronic kidney disease-mineral and bone disorderD012080EFO_1001152N25.011
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameALSEROXYLON
INN
Description
Alseroxylon (Rautensin, Rauwiloid) is a norepinephrine reuptake inhibitor that has been investigated in the treatment of hypertension and angina pectoris and as a sedative in psychoses. It was at one time approved for use in the United States, but has since been discontinued.
Classification
Small molecule
Drug class
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Identifiers
PDB
CAS-ID8001-95-4
RxCUI599
ChEMBL IDCHEMBL1201454
ChEBI ID
PubChem CID
DrugBankDB00386
UNII ID
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 62 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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18,299 adverse events reported
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