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Dextroamphetamine adipate
Delcobese (dextroamphetamine adipate) is a small molecule pharmaceutical. Dextroamphetamine adipate was first approved as Delcobese on 1982-01-01. It is known to target sodium-dependent dopamine transporter, sodium-dependent noradrenaline transporter, and trace amine-associated receptor 1.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
No data
Patent Expiration
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ATC Codes
N: Nervous system drugs
N06: Psychoanaleptics
N06B: Psychostimulants, agents used for adhd and nootropics
N06BA: Centrally acting sympathomimetics
N06BA02: Dexamfetamine
HCPCS
No data
Clinical
Clinical Trials
15 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Prostatic neoplasmsD011471C6111
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Allergic rhinitisD065631J30.922
Multiple sclerosisD009103EFO_0003885G35112
SunburnD013471EFO_0003958L5522
Insect bites and stingsD00729922
Lupus nephritisD008181EFO_000576111
Systemic lupus erythematosusD008180EFO_0002690M3211
VasoplegiaD05698711
Respiratory tract infectionsD012141J06.911
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
PainD010146EFO_0003843R5211
CognitionD003071EFO_000392511
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameDEXTROAMPHETAMINE ADIPATE
INNdexamfetamine
Description
(S)-amphetamine is a 1-phenylpropan-2-amine that has S configuration. It has a role as a neurotoxin, an adrenergic uptake inhibitor, a dopaminergic agent, a sympathomimetic agent, a dopamine uptake inhibitor and an adrenergic agent. It is an enantiomer of a (R)-amphetamine.
Classification
Small molecule
Drug class
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
C[C@H](N)Cc1ccccc1.O=C(O)CCCCC(=O)O
Identifiers
PDB
CAS-ID51-64-9
RxCUI3288
ChEMBL IDCHEMBL1200782
ChEBI ID
PubChem CID5826
DrugBankDB01576
UNII IDTZ47U051FI (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
SLC6A3
SLC6A3
SLC6A2
SLC6A2
TAAR1
TAAR1
Organism
Homo sapiens
Gene name
SLC6A3
Gene synonyms
DAT1
NCBI Gene ID
Protein name
sodium-dependent dopamine transporter
Protein synonyms
DA transporter, dopamine transporter 1, solute carrier family 6 (neurotransmitter transporter), member 3, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3, Solute carrier family 6 member 3
Uniprot ID
Mouse ortholog
Slc6a3 (13162)
sodium-dependent dopamine transporter (Q9R1I2)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 239 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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1,813 adverse events reported
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