Antihemophilic factor
Antihemophilic factor is an unknown pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
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HCPCS
Code | Description |
|---|---|
| J7180 | Injection, factor xiii (antihemophilic factor, human), 1 i.u. |
| J7182 | Injection, factor viii, (antihemophilic factor, recombinant), (novoeight), per iu |
| J7185 | Injection, factor viii (antihemophilic factor, recombinant) (xyntha), per i.u. |
| J7186 | Injection, antihemophilic factor viii/von willebrand factor complex (human), per factor viii i.u. |
| J7188 | Injection, factor viii (antihemophilic factor, recombinant), (obizur), per i.u. |
| J7189 | Factor viia (antihemophilic factor, recombinant), (novoseven rt), 1 microgram |
| J7190 | Factor viii (antihemophilic factor, human) per i.u. |
| J7191 | Factor viii (antihemophilic factor (porcine)), per i.u. |
| J7192 | Factor viii (antihemophilic factor, recombinant) per i.u., not otherwise specified |
| J7193 | Factor ix (antihemophilic factor, purified, non-recombinant) per i.u. |
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Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Atrial fibrillation | D001281 | EFO_0000275 | I48.0 | — | — | — | 2 | — | 2 |
Indications Phases 3
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Indications Phases 2
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Indications Phases 1
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Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | ANTIHEMOPHILIC FACTOR |
| INN | — |
| Description | Alphanate (antihemophilic factor) is a protein pharmaceutical. It is a lyophilized concentrate of Factor VIII (FVIII; AHF) and von Willebrand Factor (VWF). |
| Classification | Protein |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | >4KI5:C|MURINE MONOCLONAL 3E6 FAB HEAVY CHAIN
QIQLVQSGPELKKPGKTVKISCKASDYTFTDYSLHWVKQAPGKGLKWMGWINTETGDPAYADDFKGRFAFSLETSVRTAY
LQINNLKNEDTAIYFCAREDDGLASWGQGTTLTVSSAKTTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVTLTWNSG
SLSSGVHTFPAVLQSDLYTLSSSVTVTSSTWPSQSITCNVAHPASSTKVDKKIEPRGPA
>4KI5:D|MURINE MONOCLONAL 3E6 FAB LIGHT CHAIN
QIVLTQSPAIMSASPGEKVTMTCSASSTVSYMYWYQQKPGSSPRFLISDTSNLASGVPVRFSGSGSGTSYSLTISRIEAE
DAATYYCQHWSSYPLTFGGGTKLELKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVLN
SWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC
>4KI5:E|MURINE MONOCLONAL G99 FAB HEAVY CHAIN
QVQLQQSGAELMKPGASVKISCKATGYTFSSYWIEWVKQRPGHGLEWIGEILPGSGSTNYNERFKGKASFTADSSSNTAY
MQLSSLTSEDSAVYYCTRTSYYFGSSYDFDVWGAGTTVTVSSAKTTAPSVYPLAPVCGDTTGSSVTLGCLVKGYFPEPVT
LTWNSGSLSSGVHTFPALLQSDLYTLSSSVTVTSSTWPSQSITCNVAHPASSTKVDKKIEPRGP
>4KI5:F|MURINE MONOCLONAL G99 FAB LIGHT CHAIN
DIQMTQSPSSLSASLGERVSLTCRASQEISGYLSWLQQKPDGTIKRLIYAASTLDSSVPKRFSGSRSGSDYSLTISSLDS
EDFAVYYCLQYASYPYTFGGGTKVEIKRADAAPTVSIFPPSSEQLTSGGASVVCFLNNFYPKDINVKWKIDGSERQNGVL
NSWTDQDSKDSTYSMSSTLTLTKDEYERHNSYTCEATHKTSTSPIVKSFNRNEC
>4KI5:M|Coagulation factor VIII
MGSSHHHHHHSSGLVPRGSHMLNSCSMPLGMESKAISDAQITASSYFTNMFATWSPSKARLHLQGRSNAWRPQVNNPKEW
LQVDFQKTMKVTGVTTQGVKSLLTSMYVKEFLISSSQDGHQWTLFFQNGKVKVFQGNQDSFTPVVNSLDPPLLTRYLRIH
PQSWVHQIALRMEVLGCEAQDLY |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Financial
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Trends
PubMed Central
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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2 adverse events reported
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