Arbutamine
Genesa (arbutamine) is a small molecule pharmaceutical. Arbutamine was first approved as Genesa on 1997-09-12.
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Therapeutic Areas
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Trade Name
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EMA
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Arbutamine hydrochloride
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
GENESA | Gensia Automedics | N-020420 DISCN | 1997-09-12 | 1 products |
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FDA
EMA
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Indications
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Agency Specific
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EMA
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Patent Expiration
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HCPCS
Code | Description |
---|---|
J0395 | Injection, arbutamine hcl, 1 mg |
Clinical
Clinical Trials
42 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Parkinson disease | D010300 | EFO_0002508 | G20 | — | 14 | 14 | 5 | 3 | 33 |
Low back pain | D017116 | HP_0003419 | M54.5 | — | — | — | 1 | — | 1 |
Restless legs syndrome | D012148 | EFO_0004270 | G25.81 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Consciousness disorders | D003244 | — | 2 | 1 | — | — | 2 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hallucinations | D006212 | HP_0000738 | F06.0 | — | 1 | — | — | — | 1 |
Brain injuries | D001930 | S06.9 | — | 1 | — | — | — | 1 | |
Alcoholism | D000437 | EFO_0003829 | F10.1 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Progressive supranuclear palsy | D013494 | EFO_0002512 | G23.1 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common name | ARBUTAMINE |
INN | arbutamine |
Description | Arbutamine is a catecholamine. It has a role as a beta-adrenergic agonist and a cardiotonic drug. |
Classification | Small molecule |
Drug class | — |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | Oc1ccc(CCCCNC[C@H](O)c2ccc(O)c(O)c2)cc1 |
Identifiers
PDB | — |
CAS-ID | 128470-16-6 |
RxCUI | 61609 |
ChEMBL ID | CHEMBL1201251 |
ChEBI ID | 50580 |
PubChem CID | 60789 |
DrugBank | DB01102 |
UNII ID | B07L15YAEV (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
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Trends
PubMed Central
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Additional graphs summarizing 599 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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6,016 adverse events reported
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