Pac-14028
Pac-14028 is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target transient receptor potential cation channel subfamily V member 1.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
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Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
12 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Atopic dermatitis | D003876 | EFO_0000274 | L20 | 1 | 3 | 1 | — | — | 4 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | 3 | — | — | — | — | 3 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common name | PAC-14028 |
INN | asivatrep |
Description | Pac-14028 is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target transient receptor potential cation channel subfamily V member 1. |
Classification | Small molecule |
Drug class | — |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
PDB | — |
CAS-ID | 1005168-10-4 |
RxCUI | — |
ChEMBL ID | CHEMBL3707398 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | — |
UNII ID | 3VF7K7Z10B (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
TRPV1
TRPV1
Organism
Homo sapiens
Gene name
TRPV1
Gene synonyms
VR1
NCBI Gene ID
Protein name
transient receptor potential cation channel subfamily V member 1
Protein synonyms
Capsaicin receptor, Osm-9-like TRP channel 1, OTRPC1, transient receptor potential vanilloid 1a, transient receptor potential vanilloid 1b, Vanilloid receptor 1, vanilloid receptor subtype 1
Uniprot ID
Mouse ortholog
Trpv1 (193034)
transient receptor potential cation channel subfamily V member 1 (Q704Y3)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 19 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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