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Aspartame
Aspartame is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
No data
ATC Codes
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HCPCS
No data
Clinical
Clinical Trials
23 clinical trials
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Mock data
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients111
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
GastroenteritisD005759EFO_1001463K52.911
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
ObesityD009765EFO_0001073E66.966
Type 2 diabetes mellitusD003924EFO_0001360E1133
Glucose intoleranceD018149HP_0000833R73.0322
Glucose metabolism disordersD04488222
Metabolic syndromeD024821EFO_0000195E88.8122
Kidney transplantationD01603011
HyperglycemiaD006943HP_0003074R73.911
Body weightD001835EFO_000433811
Chronic diseaseD00290811
DyslipidemiasD050171HP_000311911
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameASPARTAME
INNaspartame
Description
Aspartame is a dipeptide obtained by formal condensation of the alpha-carboxy group of L-aspartic acid with the amino group of methyl L-phenylalaninate. Commonly used as an artificial sweetener. It has a role as a sweetening agent, a nutraceutical, a micronutrient, a xenobiotic, an environmental contaminant, an apoptosis inhibitor and an EC 3.1.3.1 (alkaline phosphatase) inhibitor. It is a dipeptide, a carboxylic acid and a methyl ester. It is functionally related to a L-aspartic acid and a methyl L-phenylalaninate.
Classification
Small molecule
Drug class
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
COC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CC(=O)O
Identifiers
PDB
CAS-ID22839-47-0
RxCUI1311524
ChEMBL IDCHEMBL171679
ChEBI ID2877
PubChem CID134601
DrugBankDB00168
UNII IDZ0H242BBR1 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 3,381 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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100 adverse events reported
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