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Balicatib
Balicatib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against cathepsin K.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
3 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
OsteoporosisD010024EFO_0003882M81.0—2———2
Knee osteoarthritisD020370EFO_0004616M17—1———1
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameBALICATIB
INNbalicatib
Description
Balicatib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against cathepsin K.
Classification
Small molecule
Drug classcathespin inhibitors
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCCN1CCN(c2ccc(C(=O)NC3(C(=O)NCC#N)CCCCC3)cc2)CC1
Identifiers
PDB—
CAS-ID354813-19-7
RxCUI—
ChEMBL IDCHEMBL371064
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDE00MVC7O57 (ChemIDplus, GSRS)
Target
Agency Approved
CTSK
CTSK
Organism
Homo sapiens
Gene name
CTSK
Gene synonyms
CTSO, CTSO2
NCBI Gene ID
1513
Protein name
cathepsin K
Protein synonyms
Cathepsin O, cathepsin O1, Cathepsin O2, Cathepsin X
Uniprot ID
Q6FHS6
Mouse ortholog
Ctsk (13038)
cathepsin K (P55097)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 125 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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2 adverse events reported
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