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Bapineuzumab
Bapineuzumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against amyloid-beta precursor protein.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
15 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Alzheimer diseaseD000544EFO_0000249F03167—115
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameBAPINEUZUMAB
INNbapineuzumab
Description
Bapineuzumab (humanized mab)
Classification
Antibody
Drug classmonoclonal antibodies
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID648895-38-9
RxCUI—
ChEMBL IDCHEMBL2108576
ChEBI ID—
PubChem CID—
DrugBankDB11715
UNII IDNC11WKO35D (ChemIDplus, GSRS)
Target
Agency Approved
APP
APP
Organism
Homo sapiens
Gene name
APP
Gene synonyms
A4, AD1
NCBI Gene ID
351
Protein name
amyloid-beta precursor protein
Protein synonyms
ABPP, Alzheimer disease amyloid A4 protein homolog, Alzheimer disease amyloid protein, amyloid beta (A4) precursor protein, amyloid beta A4 protein, Amyloid precursor protein, Amyloid-beta (A4) precursor protein, Amyloid-beta A4 protein, APPI, beta-amyloid peptide, beta-amyloid peptide(1-40), beta-amyloid peptide(1-42), beta-amyloid precursor protein, Cerebral vascular amyloid peptide, CVAP, peptidase nexin-II, PN-II, PreA4, Protease nexin-II, testicular tissue protein Li 2
Uniprot ID
Q9UQ58
Mouse ortholog
App (11820)
amyloid-beta precursor protein (Q99K32)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,717 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
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56 adverse events reported
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