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Benperidol
Benperidol is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target D(4) dopamine receptor and D(2) dopamine receptor.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
nervous system diseasesD009422
behavior and behavior mechanismsD001520
mental disordersD001523
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
anxiety disordersEFO_0006788D001008F41.1
dementiaHP_0000726D003704F03
depression—D003863F33.9
psychotic disorders—D011618F20.81
schizophreniaEFO_0000692D012559F20
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
N: Nervous system drugs
— N05: Psycholeptics
— N05A: Antipsychotics
— N05AD: Butyrophenone derivatives, antipsychotics
— N05AD07: Benperidol
HCPCS
No data
Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
SchizophreniaD012559EFO_0000692F20——11—2
Psychotic disordersD011618F20.81———1—1
Schizophrenia spectrum and other psychotic disordersD019967———1—1
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
DementiaD003704F03——1——1
Psychophysiologic disordersD011602F45.9——1——1
DepressionD003863F33.9——1——1
Anxiety disordersD001008EFO_0006788F41.1——1——1
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameBENPERIDOL
INNbenperidol
Description
3-[1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidinyl]-1H-benzimidazol-2-one is an aromatic ketone.
Classification
Small molecule
Drug classantipsychotics (haloperidol type)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
O=C(CCCN1CCC(n2c(=O)[nH]c3ccccc32)CC1)c1ccc(F)cc1
Identifiers
PDB—
CAS-ID2062-84-2
RxCUI1373
ChEMBL IDCHEMBL297302
ChEBI ID—
PubChem CID16363
DrugBankDB12867
UNII ID97O6X78C53 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
DRD4
DRD4
DRD2
DRD2
Organism
Homo sapiens
Gene name
DRD4
Gene synonyms
NCBI Gene ID
1815
Protein name
D(4) dopamine receptor
Protein synonyms
D(2C) dopamine receptor, Dopamine D4 receptor, seven transmembrane helix receptor
Uniprot ID
Q8NGM5
Mouse ortholog
Drd4 (13491)
D(4) dopamine receptor (Q8BXS4)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 254 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
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100 adverse events reported
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