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Bentiromide
Chymex (bentiromide) is a small molecule pharmaceutical. Bentiromide was first approved as Chymex on 1983-12-29.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Bentiromide
Tradename
Company
Number
Date
Products
CHYMEXSavage LaboratoriesN-018366 DISCN1983-12-29
1 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
V: Various drug classes in atc
— V04: Diagnostic agents
— V04C: Other diagnostic agents in atc
— V04CK: Pancreatic function test diagnostic agents
— V04CK03: Bentiromide
HCPCS
No data
Clinical
Clinical Trials
6 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
HypertensionD006973EFO_0000537I10———112
Indications Phases 3
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Indications Phases 2
No data
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients—2————2
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Left ventricular hypertrophyD017379EFO_0003896————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameBENTIROMIDE
INNbentiromide
Description
Bentiromide is the dipeptide obtained by condensation of N-benzoyl-L-tyrosine with 4-aminobenzoic acid. Used as a noninvasive screening test for exocrine pancreatic insufficiency and to monitor the adequacy of supplemental pancreatic therapy, it is given by mouth: the amount of 4-aminobenzoic acid and its metabolites excreted in the urine is taken as a measure of the chymotrypsin-secreting activity of the pancreas. It has a role as a diagnostic agent, an indicator and a reagent.
Classification
Small molecule
Drug classantihyperlipidemic, thyromimetic derivatives
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
O=C(O)c1ccc(NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)c2ccccc2)cc1
Identifiers
PDB—
CAS-ID37106-97-1
RxCUI18896
ChEMBL IDCHEMBL1200368
ChEBI ID31263
PubChem CID6957673
DrugBankDB00522
UNII ID239IF5W61J (ChemIDplus, GSRS)
Target
Agency Approved
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Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 91 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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1,617 adverse events reported
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