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Benzbromarone
Benzbromarone is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
No data
ATC Codes
M: Musculo-skeletal system drugs
— M04: Antigout preparations
— M04A: Antigout preparations
— M04AB: Preparations increasing uric acid excretion
— M04AB03: Benzbromarone
HCPCS
No data
Clinical
Clinical Trials
10 clinical trials
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Mock data
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
HyperuricemiaD033461—21227
Left ventricular dysfunctionD018487———1—1
Metabolic syndromeD024821EFO_0000195E88.81———1—1
Heart failureD006333EFO_0003144I50———1—1
Type 2 diabetes mellitusD003924EFO_0001360E11———1—1
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Asymptomatic diseasesD05807011———1
Familial primary pulmonary hypertensionD065627I27.0—1———1
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Chronic renal insufficiencyD051436N18————22
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameBENZBROMARONE
INNbenzbromarone
Description
Benzbromarone is 1-Benzofuran substituted at C-2 and C-3 by an ethyl group and a 3,5-dibromo-4-hydroxybenzoyl group respectively. An inhibitor of CYP2C9, it is used as an anti-gout medication. It has a role as a uricosuric drug. It is a member of 1-benzofurans and an aromatic ketone. It is functionally related to a 2,6-dibromophenol.
Classification
Small molecule
Drug classantiarrhythmics
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCc1oc2ccccc2c1C(=O)c1cc(Br)c(O)c(Br)c1
Identifiers
PDB—
CAS-ID3562-84-3
RxCUI1385
ChEMBL IDCHEMBL388590
ChEBI ID3023
PubChem CID2333
DrugBankDB12319
UNII ID4POG0RL69O (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,445 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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109 adverse events reported
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