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Benzimidazole
Benzimidazole is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target fMet-Leu-Phe receptor.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
P: Antiparasitic products, insecticides and repellents
— P02: Anthelmintics
— P02C: Antinematodal agents
— P02CA: Benzimidazole derivatives, antinematodal
HCPCS
No data
Clinical
Clinical Trials
3 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
InfectionsD007239EFO_0000544———1—1
Drug resistanceD004351Z16.30———1—1
Indications Phases 3
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Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Hepatic echinococcosisD004444B67.8————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameBENZIMIDAZOLE
INN—
Description
1H-benzimidazole is the 1H-tautomer of benzimidazole. It is a benzimidazole and a polycyclic heteroarene. It is a conjugate acid of a benzimidazolide. It is a tautomer of a 4H-benzimidazole, a 2H-benzimidazole and a 3aH-benzimidazole.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
c1ccc2[nH]cnc2c1
Identifiers
PDB—
CAS-ID51-17-2
RxCUI1362885
ChEMBL IDCHEMBL306226
ChEBI ID41275
PubChem CID5798
DrugBankDB02962
UNII ID—
Target
Agency Approved
No data
Alternate
FPR1
FPR1
Organism
Homo sapiens
Gene name
FPR1
Gene synonyms
NCBI Gene ID
2357
Protein name
fMet-Leu-Phe receptor
Protein synonyms
fMLP receptor, FPR, N-formyl peptide receptor, N-formylpeptide chemoattractant receptor
Uniprot ID
Q9NS48
Mouse ortholog
Fpr1 (14293)
fMet-Leu-Phe receptor (Q3UV01)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 17,028 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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5,747 adverse events reported
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