Benzquinamide
Emete-con (benzquinamide) is a small molecule pharmaceutical. Benzquinamide was first approved as Emete-con on 1982-01-01. It is used to treat nausea and vomiting in the USA. The pharmaceutical is active against prostaglandin G/H synthase 2 and D(2) dopamine receptor.
Download report
Favorite
Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| signs and symptoms pathological conditions | D013568 |
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| nausea | HP_0002018 | D009325 | R11.0 |
| vomiting | HP_0002013 | D014839 | R11.1 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
178 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Acne vulgaris | D000152 | EFO_0003894 | L70 | 9 | 4 | 23 | 42 | 18 | 96 |
| Pain | D010146 | EFO_0003843 | R52 | — | 2 | 1 | 1 | 1 | 5 |
| Pharyngitis | D010612 | R07.0 | — | — | 2 | 1 | — | 3 | |
| Postoperative pain | D010149 | G89.18 | — | — | — | 1 | 1 | 2 | |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | — | — | 1 | — | 1 |
| Toothache | D014098 | K08.89 | — | — | — | 1 | — | 1 | |
| Healthy volunteers/patients | — | — | — | — | 1 | — | 1 | ||
| Dental pins | D003772 | — | — | — | 1 | — | 1 | ||
| Skin diseases | D012871 | L00-L99 | — | — | — | 1 | — | 1 | |
| Propionibacterium acnes | D011425 | NCBITaxon_1747 | — | — | — | 1 | — | 1 |
Show 3 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ischemic stroke | D000083242 | — | — | 1 | — | — | 1 | ||
| Hyperglycemia | D006943 | HP_0003074 | R73.9 | — | — | 1 | — | — | 1 |
| Eczema | D004485 | HP_0000964 | L30.9 | — | — | 1 | — | — | 1 |
| Infections | D007239 | EFO_0000544 | — | — | 1 | — | — | 1 | |
| Chronic renal insufficiency | D051436 | N18 | — | — | 1 | — | — | 1 | |
| Gastroesophageal reflux | D005764 | EFO_0003948 | K21 | — | — | 1 | — | — | 1 |
| Dyspepsia | D004415 | EFO_0008533 | K30 | — | — | 1 | — | — | 1 |
| Abdominal pain | D015746 | R10.9 | — | — | 1 | — | — | 1 | |
| Malabsorption syndromes | D008286 | EFO_0009554 | K90 | — | — | 1 | — | — | 1 |
| Stomach diseases | D013272 | — | 1 | 1 | — | — | 1 |
Show 2 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Local anesthesia | D000772 | — | 1 | — | — | 2 | 3 | ||
| Surgical wound infection | D013530 | — | 1 | — | — | 1 | 2 | ||
| Actinic keratosis | D055623 | L57.0 | — | 1 | — | — | — | 1 | |
| Critical illness | D016638 | — | 1 | — | — | — | 1 | ||
| Cerebrovascular disorders | D002561 | EFO_0003763 | I60-I69 | — | 1 | — | — | — | 1 |
| Dental anesthesia | D000766 | 1 | 1 | — | — | — | 1 | ||
| Asthma | D001249 | EFO_0000270 | J45 | — | 1 | — | — | — | 1 |
| Otitis media | D010033 | EFO_0004992 | H66.9 | — | 1 | — | — | — | 1 |
| Gingivitis | D005891 | K05.10 | 1 | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Oral lichen planus | D017676 | 1 | — | — | — | 2 | 3 | ||
| Obesity | D009765 | EFO_0001073 | E66.9 | 1 | — | — | — | 1 | 2 |
| Oral ulcer | D019226 | HP_0000155 | 1 | — | — | — | — | 1 | |
| Staphylococcal infections | D013203 | A49.01 | 1 | — | — | — | — | 1 | |
| Rosacea | D012393 | L71 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hypotension | D007022 | EFO_0005251 | I95 | — | — | — | — | 1 | 1 |
| Orthodontic anchorage procedures | D052280 | — | — | — | — | 1 | 1 | ||
| Body weight | D001835 | EFO_0004338 | — | — | — | — | 1 | 1 | |
| Glucose metabolism disorders | D044882 | — | — | — | — | 1 | 1 | ||
| Lichen planus | D008010 | L43 | — | — | — | — | 1 | 1 | |
| Liver diseases | D008107 | EFO_0001421 | K70-K77 | — | — | — | — | 1 | 1 |
| Weight loss | D015431 | HP_0001824 | — | — | — | — | 1 | 1 | |
| Feeding behavior | D005247 | — | — | — | — | 1 | 1 | ||
| Duchenne muscular dystrophy | D020388 | — | — | — | — | 1 | 1 | ||
| Scoliosis | D012600 | EFO_0004273 | M41 | — | — | — | — | 1 | 1 |
Show 21 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | BENZQUINAMIDE |
| INN | benzquinamide |
| Description | Benzquinamide is a monocarboxylic acid amide. It has a role as an antiemetic, a sedative, a H1-receptor antagonist, a muscarinic antagonist and an antipsychotic agent. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CCN(CC)C(=O)C1CN2CCc3cc(OC)c(OC)cc3C2CC1OC(C)=O |
Identifiers
| PDB | — |
| CAS-ID | 63-12-7 |
| RxCUI | 19041 |
| ChEMBL ID | CHEMBL1201250 |
| ChEBI ID | 27662 |
| PubChem CID | 2342 |
| DrugBank | DB00767 |
| UNII ID | 0475EA27Q3 (ChemIDplus, GSRS) |
Target
Agency Approved
PTGS2
PTGS2
DRD2
DRD2
Organism
Homo sapiens
Gene name
PTGS2
Gene synonyms
COX2
NCBI Gene ID
Protein name
prostaglandin G/H synthase 2
Protein synonyms
COX-2, cyclooxygenase 2, cyclooxygenase 2b, Cyclooxygenase-2, PGH synthase 2, PGHS-2, PHS II, Prostaglandin H2 synthase 2, Prostaglandin-endoperoxide synthase 2, prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
Uniprot ID
Mouse ortholog
Ptgs2 (19225)
prostaglandin G/H synthase 2 (Q543K3)
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 34 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
2,814 adverse events reported
View more details
Premium feature
Learn more about premium features at pharmakb.com
Learn more