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Brimapitide
Brimapitide is a protein pharmaceutical. It is currently being investigated in clinical studies. It is known to target mitogen-activated protein kinase 10.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
6 clinical trials
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Mock data
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Hearing lossD034381EFO_0004238H91.9—12——3
InflammationD0072491—2——3
PainD010146EFO_0003843R52——2——2
CataractD002386EFO_0001059H26.9——2——2
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameBRIMAPITIDE
INNbrimapitide
Description
Brimapitide is a protein pharmaceutical. It is currently being investigated in clinical studies. It is known to target mitogen-activated protein kinase 10.
Classification
Protein
Drug classpeptides
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CC(C)C[C@@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H]1CCCN1C(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](NC(=O)[C@H]1CCCN1C(=O)[C@@H](CCCNC(=N)N)NC(=O)[C@@H](CO)NC(=O)[C@@H](CCC(N)=O)NC(=O)[C@H](N)CC(=O)O)C(C)C)C(=O)N[C@H](CC(N)=O)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](C(=O)N[C@@H](C(=O)N1CCC[C@@H]1C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCCN)C(=O)N1CCC[C@@H]1C(=O)N[C@H](CCCNC(=N)N)C(=O)N1CCC[C@@H]1C(=O)N1CCC[C@@H]1C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCCNC(=N)N)C(=O)NCC(N)=O)[C@H](C)O)[C@H](C)O
Identifiers
PDB—
CAS-ID1445179-97-4
RxCUI—
ChEMBL IDCHEMBL4297650
ChEBI ID—
PubChem CID—
DrugBank—
UNII ID2K30142185 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
MAPK10
MAPK10
Organism
Homo sapiens
Gene name
MAPK10
Gene synonyms
JNK3, JNK3A, PRKM10, SAPK1B
NCBI Gene ID
5602
Protein name
mitogen-activated protein kinase 10
Protein synonyms
c-Jun N-terminal kinase 3, JNK3 alpha protein kinase, MAP kinase 10, MAP kinase p49 3F12, SAPK1b, stress activated protein kinase beta, Stress-activated protein kinase 1b, Stress-activated protein kinase JNK3
Uniprot ID
P53779
Mouse ortholog
Mapk10 (26414)
mitogen-activated protein kinase 10 (Q61831)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 24 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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