Bromelains
Bromelains is an unknown pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
D: Dermatologicals
— D03: Preparations for treatment of wounds and ulcers
— D03B: Enzymes for treatment of wounds and ulcers
— D03BA: Proteolytic enzymes for treatment of wounds and ulcers
— D03BA03: Bromelains
M: Musculo-skeletal system drugs
— M09: Other drugs for disorders of the musculo-skeletal system in atc
— M09A: Other drugs for disorders of the musculo-skeletal system in atc
— M09AB: Enzymes for disorders of the musculo-skeletal system
— M09AB03: Bromelains
HCPCS
No data
Clinical
Clinical Trials
13 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Covid-19 | D000086382 | U07.1 | 1 | 1 | — | 1 | — | 2 | |
| Postoperative pain | D010149 | G89.18 | — | — | — | 1 | 1 | 2 | |
| Male breast neoplasms | D018567 | — | — | — | 1 | — | 1 |
Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pseudomyxoma peritonei | D011553 | EFO_0007456 | 1 | 1 | — | — | — | 2 | |
| Dental caries | D003731 | EFO_0003819 | K02 | — | 1 | — | — | — | 1 |
| Dental plaque | D003773 | — | 1 | — | — | — | 1 | ||
| Neoplasms | D009369 | C80 | — | 1 | — | — | — | 1 | |
| Mucinous adenocarcinoma | D002288 | — | 1 | — | — | — | 1 | ||
| Peritoneal neoplasms | D010534 | — | 1 | — | — | — | 1 | ||
| Respiratory distress syndrome | D012128 | EFO_1000637 | J80 | 1 | 1 | — | — | — | 1 |
| Ventilator-associated pneumonia | D053717 | EFO_1001865 | J95.851 | 1 | 1 | — | — | — | 1 |
| Pneumonia | D011014 | EFO_0003106 | J18 | 1 | 1 | — | — | — | 1 |
| Pulpitis | D011671 | EFO_1001139 | K04.0 | — | 1 | — | — | — | 1 |
Indications Phases 1
No data
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Wound healing | D014945 | GO_0042060 | — | — | — | — | 1 | 1 | |
| Cardiovascular diseases | D002318 | EFO_0000319 | I98 | — | — | — | — | 1 | 1 |
| Edema | D004487 | R60.9 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | BROMELAINS |
| INN | bromelains |
| Description | Bromelain is an enzyme extract derived from the stems of pineapples, although it exists in all parts of the fresh pineapple. The extract has a history of folk medicine use. As an ingredient, it is used in cosmetics, as a topical medication, and as a meat tenderizer.
|
| Classification | Unknown |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2109027 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | U182GP2CF3 (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Financial
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 204 documents
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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35 adverse events reported
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