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Carbenicillin
Geopen, Pyopen (carbenicillin) is a small molecule pharmaceutical. Carbenicillin was first approved as Pyopen on 1982-01-01. It is used to treat bacterial infections, gram-negative bacterial infections, prostatitis, and urinary tract infections in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
urogenital diseasesD000091642
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Carbenicillin disodium
Tradename
Company
Number
Date
Products
PYOPENGSKN-050298 DISCN1982-01-01
5 products
GEOPENRoerigN-050306 DISCN1982-01-01
5 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
bacterial infections—D001424A49
gram-negative bacterial infections—D016905—
prostatitisEFO_0003830D011472N41
urinary tract infectionsEFO_0003103D014552N39.0
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01C: Beta-lactam antibacterials, penicillins
— J01CA: Penicillins with extended spectrum
— J01CA03: Carbenicillin
HCPCS
No data
Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Hiv infectionsD015658EFO_0000764B20————22
TuberculosisD014376EFO_0000774A15-A19————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCARBENICILLIN
INNcarbenicillin
Description
Carbenicillin is a penicillin antibiotic having a 6beta-2-carboxy-2-phenylacetamido side-chain. It has a role as an antibacterial drug. It is a penicillin and a penicillin allergen. It is a conjugate acid of a carbenicillin(2-).
Classification
Small molecule
Drug classpenicillins
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CC1(C)S[C@@H]2[C@H](NC(=O)C(C(=O)O)c3ccccc3)C(=O)N2[C@H]1C(=O)O
Identifiers
PDB—
CAS-ID4697-36-3
RxCUI2015
ChEMBL IDCHEMBL1214
ChEBI ID3393
PubChem CID20824
DrugBankDB00578
UNII IDG42ZU72N5G (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 17,113 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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408 adverse events reported
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