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Carlumab
Carlumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target C-C motif chemokine 2.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
4 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Prostatic neoplasmsD011471C61—1———1
Pulmonary fibrosisD011658J84.10—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeoplasmsD009369C802————2
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCARLUMAB
INNcarlumab
Description
Carlumab (human mab)
Classification
Antibody
Drug classmonoclonal antibodies
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID915404-94-3
RxCUI—
ChEMBL IDCHEMBL1742999
ChEBI ID—
PubChem CID—
DrugBankDB12718
UNII ID6TC1BB2EV9 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
CCL2
CCL2
Organism
Homo sapiens
Gene name
CCL2
Gene synonyms
MCP1, SCYA2
NCBI Gene ID
6347
Protein name
C-C motif chemokine 2
Protein synonyms
chemokine (C-C motif) ligand 2, HC11, MCAF, MCP-1, Monocyte chemoattractant protein 1, monocyte chemoattractant protein-1, Monocyte chemotactic and activating factor, Monocyte chemotactic protein 1, Monocyte secretory protein JE, small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je), small inducible cytokine subfamily A (Cys-Cys), member 2, Small-inducible cytokine A2
Uniprot ID
Q9UDF3
Mouse ortholog
Ccl2 (20296)
C-C motif chemokine 2 (Q9QYD7)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 387 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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4 adverse events reported
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