Carotuximab
Carotuximab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against endoglin.
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Abbreviated New Drug Application (ANDA)
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Clinical
Clinical Trials
28 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hemangiosarcoma | D006394 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 2 | 3 | — | — | — | 3 |
| Glioblastoma | D005909 | EFO_0000515 | 1 | 3 | — | — | — | 3 | |
| Renal cell carcinoma | D002292 | 1 | 2 | — | — | — | 2 | ||
| Choriocarcinoma | D002822 | C58 | — | 2 | — | — | — | 2 | |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 2 | 2 | — | — | — | 2 |
| Macular degeneration | D008268 | EFO_0001365 | H35.30 | 1 | 2 | — | — | — | 2 |
| Prostatic neoplasms | D011471 | C61 | 1 | 2 | — | — | — | 2 | |
| Castration-resistant prostatic neoplasms | D064129 | 1 | 2 | — | — | — | 2 | ||
| Placental site trophoblastic tumor | D018245 | — | 1 | — | — | — | 1 | ||
| Gestational trophoblastic disease | D031901 | O01.9 | — | 1 | — | — | — | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | CAROTUXIMAB |
| INN | carotuximab |
| Description | TRC-105 (chimeric mab) |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2109321 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | YB2EWE6139 (ChemIDplus, GSRS) |
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Safety
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1 adverse events reported
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