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Cefmetazole
Zefazone (cefmetazole) is a small molecule pharmaceutical. Cefmetazole was first approved as Zefazone on 1989-12-11. It is used to treat bacterial infections, escherichia coli infections, klebsiella infections, proteus infections, and serratia infections in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Cefmetazole sodium
Tradename
Company
Number
Date
Products
ZEFAZONEPharmacia & UpjohnN-050637 DISCN1989-12-11
2 products, RLD
ZEFAZONE IN PLASTIC CONTAINERPharmacia & UpjohnN-050683 DISCN1992-12-29
2 products, RLD
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
bacterial infectionsD001424A49
escherichia coli infectionsEFO_1001318D004927B96.20
klebsiella infectionsEFO_1001353D007710
proteus infectionsEFO_1001130D011512
serratia infectionsEFO_1001421D016868
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
J01: Antibacterials for systemic use
J01D: Other beta-lactam antibacterials in atc
J01DC: Second-generation cephalosporins
J01DC09: Cefmetazole
HCPCS
No data
Clinical
Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCEFMETAZOLE
INNcefmetazole
Description
Cefmetazole is a second-generation cephalosporin antibiotic having N(1)-methyltetrazol-5-ylthiomethyl, {[(cyanomethyl)sulfanyl]acetyl}amino and methoxy side-groups at positions 3, 7beta and 7alpha respectively of the parent cephem bicyclic structure. It has a role as an antibacterial drug. It is a conjugate acid of a cefmetazole(1-).
Classification
Small molecule
Drug classcephalosporins
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CO[C@@]1(NC(=O)CSCC#N)C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CS[C@@H]21
Identifiers
PDB
CAS-ID56796-20-4
RxCUI2182
ChEMBL IDCHEMBL1201195
ChEBI ID3489
PubChem CID42008
DrugBankDB00274
UNII ID3J962UJT8H (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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14 adverse events reported
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