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Ceforanide
Precef (ceforanide) is a small molecule pharmaceutical. Ceforanide was first approved as Precef on 1984-05-24. It is used to treat bacterial infections, bacterial pneumonia, escherichia coli infections, haemophilus infections, and klebsiella infections amongst others in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
respiratory tract diseasesD012140
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Ceforanide
Tradename
Company
Number
Date
Products
PRECEFBristol Myers SquibbN-050554 DISCN1984-05-24
5 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
bacterial infections—D001424A49
bacterial pneumoniaEFO_1001272D018410J15.9
escherichia coli infectionsEFO_1001318D004927B96.20
haemophilus infectionsEFO_1001127D006192—
klebsiella infectionsEFO_1001353D007710—
proteus infectionsEFO_1001130D011512—
salmonella infectionsEFO_1001418D012480A02.9
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01D: Other beta-lactam antibacterials in atc
— J01DC: Second-generation cephalosporins
— J01DC11: Ceforanide
HCPCS
No data
Clinical
Indications Phases 4
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Indications Phases 3
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Indications Phases 2
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Indications Phases 1
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Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCEFORANIDE
INNceforanide
Description
Ceforanide is a second-generation cephalosporin antibiotic with {[1-(carboxymethyl)-1H-tetrazol-5-yl]sulfanyl}methyl and 2-(aminomethyl)phenylacetamido groups at positions 3 and 7, respectively, of the cephem skeleton. It is effective against many coliforms, including Escherichia coli, Klebsiella, Enterobacter and Proteus, and most strains of Salmonella, Shigella, Hemophilus, Citrobacter and Arizona species. It has a role as an antibacterial drug.
Classification
Small molecule
Drug classcephalosporins
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
NCc1ccccc1CC(=O)N[C@@H]1C(=O)N2C(C(=O)O)=C(CSc3nnnn3CC(=O)O)CS[C@H]12
Identifiers
PDB—
CAS-ID60925-61-3
RxCUI20486
ChEMBL IDCHEMBL1201046
ChEBI ID3495
PubChem CID43507
DrugBankDB00923
UNII ID8M1YF8951V (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 154 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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120 adverse events reported
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