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Cephapirin
Cefadyl (cephapirin) is a small molecule pharmaceutical. Cephapirin was first approved as Cefadyl on 1982-01-01. It is used to treat bacterial skin diseases, escherichia coli infections, klebsiella infections, proteus infections, and respiratory tract infections amongst others in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
respiratory tract diseasesD012140
urogenital diseasesD000091642
skin and connective tissue diseasesD017437
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Cephapirin sodium
Tradename
Company
Number
Date
Products
CEFADYLBristol Myers SquibbN-050446 DISCN1982-01-01
5 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
bacterial skin diseases—D017192—
escherichia coli infectionsEFO_1001318D004927B96.20
klebsiella infectionsEFO_1001353D007710—
proteus infectionsEFO_1001130D011512—
respiratory tract infections—D012141J06.9
soft tissue infections—D018461—
staphylococcal infections—D013203A49.01
streptococcal infectionsEFO_1001476D013290—
urinary tract infectionsEFO_0003103D014552N39.0
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01D: Other beta-lactam antibacterials in atc
— J01DB: First-generation cephalosporins
— J01DB08: Cefapirin
HCPCS
Code
Description
J0710
Injection, cephapirin sodium, up to 1 gm
Clinical
Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCEPHAPIRIN
INNcefapirin
Description
Cephapirin is a cephalosporin with acetoxymethyl and 2(pyridin-4-ylsulfanyl)acetamido substituents at positions 3 and 7, respectively, of the cephem skeleton. It is used (as its sodium salt) as an antibiotic, being effective against gram-negative and gram-positive organisms. It has a role as an antibacterial drug. It is a conjugate acid of a cephapirin(1-).
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CC(=O)OCC1=C(C(=O)O)N2C(=O)[C@@H](NC(=O)CSc3ccncc3)[C@H]2SC1
Identifiers
PDB—
CAS-ID21593-23-7
RxCUI2238
ChEMBL IDCHEMBL1599
ChEBI ID554446
PubChem CID30699
DrugBankDB01139
UNII ID89B59H32VN (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 597 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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80 adverse events reported
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