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Cetilistat
Cetilistat is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target pancreatic triacylglycerol lipase.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
2 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
ObesityD009765EFO_0001073E66.911———2
Type 2 diabetes mellitusD003924EFO_0001360E11—1———1
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCETILISTAT
INNcetilistat
Description
Cetilistat is a benzoxazine.
Classification
Small molecule
Drug classenzyme inhibitors: gastrointestinal lipase inhibitors
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CCCCCCCCCCCCCCCCOc1nc2ccc(C)cc2c(=O)o1
Identifiers
PDB—
CAS-ID282526-98-1
RxCUI—
ChEMBL IDCHEMBL2103825
ChEBI ID—
PubChem CID9952916
DrugBankDB06586
UNII IDLC5G1JUA39 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
PNLIP
PNLIP
Organism
Homo sapiens
Gene name
PNLIP
Gene synonyms
NCBI Gene ID
5406
Protein name
pancreatic triacylglycerol lipase
Protein synonyms
triacylglycerol acylhydrolase, triacylglycerol lipase
Uniprot ID
Q5VSQ2
Mouse ortholog
Pnlip (69060)
pancreatic triacylglycerol lipase (Q6P8U6)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 114 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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