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Chlophedianol
Ulo (chlophedianol) is a small molecule pharmaceutical. Chlophedianol was first approved as Ulo on 1982-01-01.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Chlophedianol hydrochloride
Tradename
Company
Number
Date
Products
ULO3MN-012126 DISCN1982-01-01
1 products
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Labels
FDA
EMA
Brand Name
Status
Last Update
chlo histOTC monograph final2023-06-19
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
R: Respiratory system drugs
— R05: Cough and cold preparations
— R05D: Cough suppressants, excl. combinations with expectorants
— R05DB: Other cough suppressants in atc
— R05DB10: Clofedanol
HCPCS
No data
Clinical
Clinical Trials
5 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
XerostomiaD014987K11.7———1—1
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Head and neck neoplasmsD006258——1——1
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCHLOPHEDIANOL
INNclofedanol
Description
Clofedanol is a diarylmethane that is 2-chlorophenyl(phenyl)methane substituted on the methane carbon by a 2-(dimethylamino)ethyl group. Used in the treatment of dry cough, it suppresses the cough reflex by a direct effect on the cough centre in the medulla of the brain. It has a role as an antitussive. It is a diarylmethane and a tertiary amino compound. It is a conjugate base of a clofedanol(1+).
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CN(C)CCC(O)(c1ccccc1)c1ccccc1Cl
Identifiers
PDB—
CAS-ID791-35-5
RxCUI21254
ChEMBL IDCHEMBL1201313
ChEBI ID—
PubChem CID2795
DrugBankDB04837
UNII ID42C50P12AP (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 14 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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497 adverse events reported
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