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Chlorprothixene
Taractan (chlorprothixene) is a small molecule pharmaceutical. Chlorprothixene was first approved as Taractan on 1982-01-01. It is used to treat paranoid schizophrenia and psychotic disorders in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
mental disordersD001523
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Chlorprothixene
Tradename
Company
Number
Date
Products
TARACTANRocheN-012486 DISCN1982-01-01
4 products
TARACTANRocheN-012487 DISCN1982-01-01
1 products
TARACTANRocheN-016149 DISCN1982-01-01
1 products
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Labels
FDA
EMA
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Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
paranoid schizophreniaD012563F20.0
psychotic disordersD011618F20.81
Agency Specific
FDA
EMA
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Patent Expiration
No data
ATC Codes
N: Nervous system drugs
N05: Psycholeptics
N05A: Antipsychotics
N05AF: Thioxanthene derivatives, antipsychotic
N05AF03: Chlorprothixene
HCPCS
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Clinical
Clinical Trials
1 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
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Indications Phases 1
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Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Diabetes insipidusD003919E23.211
Neurogenic diabetes insipidusD020790HP_000086311
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCHLORPROTHIXENE
INNchlorprothixene
Description
Chlorprothixene is a member of thioxanthenes, a tertiary amino compound and an organochlorine compound. It has a role as a non-narcotic analgesic, an antiemetic, a sedative, a cholinergic antagonist, a dopaminergic antagonist and a first generation antipsychotic. It is a conjugate base of a chlorprothixene(1+).
Classification
Small molecule
Drug classTypical antipsychotic
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CN(C)CC/C=C1/c2ccccc2Sc2ccc(Cl)cc21
Identifiers
PDB
CAS-ID113-59-7
RxCUI2406
ChEMBL IDCHEMBL908
ChEBI ID50931
PubChem CID667466
DrugBankDB01239
UNII ID9S7OD60EWP (ChemIDplus, GSRS)
Target
Agency Approved
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Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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118 adverse events reported
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