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Ciprofibrate
Ciprofibrate is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target peroxisome proliferator-activated receptor alpha.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
C: Cardiovascular system drugs
— C10: Lipid modifying agents
— C10A: Lipid modifying agents, plain
— C10AB: Fibrates, lipid modifying drugs, plain
— C10AB08: Ciprofibrate
HCPCS
No data
Clinical
Clinical Trials
3 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
HypertensionD006973EFO_0000537I10———2—2
DyslipidemiasD050171HP_0003119———1—1
HypertriglyceridemiaD015228EFO_0004211———1—1
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Glucose metabolism disordersD044882——1——1
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameCIPROFIBRATE
INNciprofibrate
Description
Ciprofibrate is a monocarboxylic acid, a member of cyclopropanes and an organochlorine compound. It has a role as an antilipemic drug.
Classification
Small molecule
Drug classantihyperlipidemics (clofibrate type)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CC(C)(Oc1ccc(C2CC2(Cl)Cl)cc1)C(=O)O
Identifiers
PDB6LX5
CAS-ID52214-84-3
RxCUI21149
ChEMBL IDCHEMBL557555
ChEBI ID50867
PubChem CID2763
DrugBankDB09064
UNII IDF8252JGO9S (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
PPARA
PPARA
Organism
Homo sapiens
Gene name
PPARA
Gene synonyms
NR1C1, PPAR
NCBI Gene ID
5465
Protein name
peroxisome proliferator-activated receptor alpha
Protein synonyms
Nuclear receptor subfamily 1 group C member 1, peroxisome proliferative activated receptor, alpha
Uniprot ID
Q9Y3N1
Mouse ortholog
Ppara (19013)
peroxisome proliferator-activated receptor alpha (P23204)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 873 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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90 adverse events reported
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