Clesacostat
Clesacostat is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target acetyl-CoA carboxylase 2 and acetyl-CoA carboxylase 1.
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Therapeutic Areas
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Trade Name
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Drug Products
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EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
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Indications
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Agency Specific
FDA
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Patent Expiration
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ATC Codes
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HCPCS
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Clinical
Clinical Trials
11 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-alcoholic fatty liver disease | D065626 | EFO_0003095 | K75.81 | 1 | 4 | — | — | — | 5 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 4 | — | — | — | — | 4 | ||
| Hepatic insufficiency | D048550 | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | CLESACOSTAT |
| INN | clesacostat |
| Description | Clesacostat is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target acetyl-CoA carboxylase 2 and acetyl-CoA carboxylase 1. |
| Classification | Small molecule |
| Drug class | enzyme inhibitors: acetyl CoA carboxylase (ACC) inhibitors |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | COc1cc(C(=O)N2CCC3(CC2)CC(=O)c2c(cnn2C(C)C)C3)cc(-c2ccc(C(=O)O)cc2)n1 |
Identifiers
| PDB | — |
| CAS-ID | 1370448-25-1 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4567446 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 752DF9PPPI (ChemIDplus, GSRS) |
Target
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Clinical Variant
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Trends
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Additional graphs summarizing 7 documents
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Safety
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Adverse Events
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0 adverse events reported
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