Clivatuzumab tetraxetan
Clivatuzumab tetraxetan is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target mucin-1.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
4 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 3 | 2 | 1 | — | — | 4 |
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common name | CLIVATUZUMAB TETRAXETAN |
INN | clivatuzumab tetraxetan |
Description | Clivatuzumab tetraxetan (humanized mab) |
Classification | Antibody |
Drug class | monoclonal antibodies; chelating agents |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
PDB | — |
CAS-ID | 943976-23-6 |
RxCUI | — |
ChEMBL ID | CHEMBL3301586 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | DB15368 |
UNII ID | 1D1F7UG35J (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
MUC1
MUC1
Organism
Homo sapiens
Gene name
MUC1
Gene synonyms
PUM
NCBI Gene ID
Protein name
mucin-1
Protein synonyms
Breast carcinoma-associated antigen DF3, CA 15-3, Cancer antigen 15-3, Carcinoma-associated mucin, CD227, EMA, Episialin, H23 antigen, H23AG, KL-6, Krebs von den Lungen-6, mucin 1, transmembrane, Peanut-reactive urinary mucin, PEM, PEMT, Polymorphic epithelial mucin, PUM, tumor associated epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin
Uniprot ID
Mouse ortholog
Muc1 (17829)
mucin-1 (Q02496)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 33 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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5 adverse events reported
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