Colestipol hydrochloride
Colestid (colestipol hydrochloride) is an unknown pharmaceutical. Colestipol hydrochloride was first approved as Flavored colestid on 1982-01-01. It is used to treat coronary artery disease, diarrhea, hypercholesterolemia, hyperlipoproteinemias, and hypertriglyceridemia amongst others in the USA.
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Commercial
Trade Name
FDA
EMA
Colestid, Flavored colestid (generic drugs available since 2006-05-02)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| colestid | New Drug Application | 2022-11-16 |
| colestipol hydrochloride | ANDA | 2023-04-26 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| coronary artery disease | — | D003324 | I25.1 |
| diarrhea | HP_0002014 | D003967 | R19.7 |
| hypercholesterolemia | HP_0003124 | D006937 | — |
| hyperlipoproteinemias | — | D006951 | — |
| hypertriglyceridemia | EFO_0004211 | D015228 | — |
| pseudomembranous enterocolitis | EFO_1001314 | D004761 | A04.7 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
No data
Clinical
Clinical Trials
67 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Schizophrenia | D012559 | EFO_0000692 | F20 | 3 | 2 | 6 | 25 | 13 | 48 |
| Psychotic disorders | D011618 | F20.81 | — | 1 | — | 14 | 3 | 18 | |
| Bipolar disorder | D001714 | EFO_0000289 | F30.9 | — | 1 | 2 | 2 | 2 | 7 |
| Substance-related disorders | D019966 | EFO_0003890 | F13 | — | — | — | 2 | 1 | 3 |
| Dual (psychiatry) diagnosis | D017831 | — | — | — | 3 | — | 3 | ||
| Marijuana abuse | D002189 | EFO_0007191 | F12 | — | — | — | 2 | 1 | 3 |
| Metabolic syndrome | D024821 | EFO_0000195 | E88.81 | — | — | — | 1 | — | 1 |
| Alcoholism | D000437 | EFO_0003829 | F10.1 | — | — | — | 1 | — | 1 |
| Panic disorder | D016584 | EFO_0004262 | F41.0 | — | — | — | 1 | — | 1 |
| Childhood schizophrenia | D012561 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Intellectual disability | D008607 | F73 | — | 1 | 1 | — | — | 2 | |
| Dementia | D003704 | F03 | — | — | 1 | — | — | 1 | |
| Psychophysiologic disorders | D011602 | F45.9 | — | — | 1 | — | — | 1 | |
| Depression | D003863 | F33.9 | — | — | 1 | — | — | 1 | |
| Anxiety disorders | D001008 | EFO_0006788 | F41.1 | — | — | 1 | — | — | 1 |
| Developmental disabilities | D002658 | EFO_0003852 | F89 | — | — | 1 | — | — | 1 |
| Tic disorders | D013981 | F95 | — | — | 1 | — | — | 1 | |
| Major depressive disorder | D003865 | EFO_0003761 | F22 | — | — | 1 | — | — | 1 |
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Leukemia | D007938 | C95 | — | — | — | — | 1 | 1 | |
| Lymphoma | D008223 | C85.9 | — | — | — | — | 1 | 1 | |
| Weight gain | D015430 | HP_0004324 | — | — | — | — | 1 | 1 | |
| Sialorrhea | D012798 | HP_0002307 | K11.7 | — | — | — | — | 1 | 1 |
| Parkinson disease | D010300 | EFO_0002508 | G20 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | COLESTIPOL HYDROCHLORIDE |
| INN | colestipol |
| Description | Colestipol (trade names Colestid, Cholestabyl) is a bile acid sequestrant used to lower blood cholesterol, specifically low-density lipoprotein (LDL). It is also used to reduce stool volume and frequency, and in the treatment of chronic diarrhea.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | ClCC1CO1.NCCNCCNCCNCCN |
Identifiers
| PDB | — |
| CAS-ID | 26658-42-4 |
| RxCUI | 2685 |
| ChEMBL ID | CHEMBL1201474 |
| ChEBI ID | — |
| PubChem CID | 62816 |
| DrugBank | DB00375 |
| UNII ID | K50N755924 (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,091 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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87,862 adverse events reported
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