Dapirolizumab pegol
Dapirolizumab pegol is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target CD40 ligand.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
5 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Systemic lupus erythematosus | D008180 | EFO_0002690 | M32 | 2 | 1 | 1 | — | — | 4 |
Indications Phases 2
No data
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Connective tissue diseases | D003240 | EFO_1001986 | M35 | 2 | — | — | — | — | 2 |
| Immune system diseases | D007154 | D89.9 | 2 | — | — | — | — | 2 | |
| Autoimmune diseases | D001327 | EFO_0000540 | M30-M36 | 2 | — | — | — | — | 2 |
| Skin and connective tissue diseases | D017437 | 2 | — | — | — | — | 2 | ||
| Healthy volunteers/patients | — | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | DAPIROLIZUMAB PEGOL |
| INN | dapirolizumab pegol |
| Description | CDP-7657 (mab) |
| Classification | Antibody |
| Drug class | monoclonal antibodies; PEGylated compounds, covalent attachment of macrogol (polyethylene glycol) polymer |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2109478 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | N4606MB5HM (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
CD40LG
CD40LG
Organism
Homo sapiens
Gene name
CD40LG
Gene synonyms
CD40L, TNFSF5, TRAP
NCBI Gene ID
Protein name
CD40 ligand
Protein synonyms
CD154, CD40 antigen ligand, CD40-L, T-B cell-activating molecule, T-cell antigen Gp39, TNF-related activation protein, TRAP, tumor necrosis factor (ligand) superfamily member 5, Tumor necrosis factor ligand superfamily member 5
Uniprot ID
Mouse ortholog
Cd40lg (21947)
CD40 ligand (P27548)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 64 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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