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Desflurane
Suprane (desflurane) is a small molecule pharmaceutical. Desflurane was first approved as Suprane on 1992-09-18. It is used to treat pain in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
signs and symptoms pathological conditionsD013568
psychological phenomenaD011579
musculoskeletal and neural physiological phenomenaD055687
Trade Name
FDA
EMA
Suprane (generic drugs available since 2018-02-26)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Desflurane
Tradename
Company
Number
Date
Products
SUPRANEBaxterN-020118 RX1992-09-18
1 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
supraneNew Drug Application2023-02-22
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
painEFO_0003843D010146R52
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
N: Nervous system drugs
— N01: Anesthetics
— N01A: Anesthetics, general
— N01AB: Halogenated hydrocarbons, general anesthetics
— N01AB07: Desflurane
HCPCS
No data
Clinical
Clinical Trials
55 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Visceral leishmaniasisD007898B55.0——3216
AdiposityD0501541——2—3
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients—713——11
InfectionsD007239EFO_0000544——2——2
CandidiasisD002177B37——1——1
AspergillosisD001228EFO_0007157B44——1——1
LeukemiaD007938C95——1——1
Myelodysplastic syndromesD009190D46——1——1
Myeloproliferative disordersD009196D47.1——1——1
LymphomaD008223C85.9——1——1
Plasma cell neoplasmsD054219——1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
LipomaD008067D17.911———2
Invasive candidiasisD058365EFO_1001283B37—1———1
Ovarian neoplasmsD010051EFO_0003893C5611———1
Endometrioid carcinomaD01826911———1
Fallopian tube neoplasmsD00518511———1
LeiomyosarcomaD007890—1———1
LiposarcomaD008080—1———1
Postoperative painD010149G89.18—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Cryptococcal meningitisD016919EFO_0007228B45.11———12
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
ObesityD009765EFO_0001073E66.9————11
MycosesD009181B35-B49————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameDESFLURANE
INNdesflurane
Description
Desflurane is an organofluorine compound. It has a role as an inhalation anaesthetic. It is functionally related to a methoxyethane.
Classification
Small molecule
Drug classgeneral inhalation anesthetics (halogenated alkane derivatives)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
FC(F)OC(F)C(F)(F)F
Identifiers
PDB—
CAS-ID57041-67-5
RxCUI27340
ChEMBL IDCHEMBL1200733
ChEBI ID4445
PubChem CID42113
DrugBankDB01189
UNII IDCRS35BZ94Q (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
Identifier
Target mutation
Effect
Evaluation
Status
VCV000575733CACNA1S, 520C>T, Arg174Trpdrug response2021-03-241A
VCV000017626CACNA1S, 3257G>A, Arg1086Hisdrug response2021-03-241A
VCV000012984RYR1, 14545G>A, Val4849Iledrug response2021-03-241A
VCV000012972RYR1, 7373G>A, Arg2458Hisdrug response2021-03-241A
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 6,231 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
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3,111 adverse events reported
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