Desonide
Desowen, Tridesilon, Verdeso (desonide) is a small molecule pharmaceutical. Desonide was first approved as Tridesilon on 1982-01-01. It is used to treat facial dermatoses, foot dermatoses, hand dermatoses, inflammation, and leg dermatoses amongst others in the USA.
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Commercial
Trade Name
FDA
EMA
Desowen, Verdeso (generic drugs available since 1988-06-15, discontinued: Desonate)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Acetic acid
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glacial
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Desonide
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
TRIDESILON | Bayer | N-017914 DISCN | 1982-01-01 | 1 products |
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Labels
FDA
EMA
Brand Name | Status | Last Update |
---|---|---|
desonate | New Drug Application | 2010-11-08 |
desonide | ANDA | 2023-03-03 |
desowen | ANDA, New Drug Application | 2019-01-28 |
tridesilon cream | New Drug Application | 2016-04-21 |
verdeso | New Drug Application | 2020-04-29 |
Agency Specific
FDA
EMA
No data
ATC Codes
D: Dermatologicals
— D07: Corticosteroids, dermatological preparations
— D07A: Corticosteroid dermatological preparations, plain
— D07AB: Corticosteroids, moderately potent (group ii)
— D07AB08: Desonide
— D07B: Corticosteroids, combinations with antiseptics
— D07BB: Corticosteroids, moderately potent, combinations with antiseptics
— D07BB02: Desonide and antiseptics
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01B: Antiinflammatory agents, ophthalmologic
— S01BA: Corticosteroid ophthalmologic antiinflammatory agents, plain
— S01BA11: Desonide
HCPCS
Code | Description |
---|---|
J7626 | Budesonide, inhalation solution, fda-approved final product, non-compounded, administered through dme, unit dose form, up to 0.5 mg |
J7627 | Budesonide, inhalation solution, compounded product, administered through dme, unit dose form, up to 0.5 mg |
J7633 | Budesonide, inhalation solution, fda-approved final product, non-compounded, administered through dme, concentrated form, per 0.25 milligram |
J7634 | Budesonide, inhalation solution, compounded product, administered through dme, concentrated form, per 0.25 milligram |
Clinical
Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common name | DESONIDE |
INN | desonide |
Description | Desonide is triamcinolone acetonide with hydrogen instead of the fluorine substituent at position 9. A corticosteroid anti-inflammatory, it is used topically as a cream, ointment or lotion for the treatment of various skin disorders. It has a role as an anti-inflammatory drug. It is an 11beta-hydroxy steroid, a 21-hydroxy steroid, a 20-oxo steroid, a corticosteroid, a cyclic ketal, a 3-oxo-Delta(1),Delta(4)-steroid and a primary alpha-hydroxy ketone. |
Classification | Small molecule |
Drug class | topical steroids (acetal derivatives) |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | CC1(C)O[C@@H]2C[C@H]3[C@@H]4CCC5=CC(=O)C=C[C@]5(C)[C@H]4[C@@H](O)C[C@]3(C)[C@]2(C(=O)CO)O1 |
Identifiers
PDB | — |
CAS-ID | 638-94-8 |
RxCUI | 3254 |
ChEMBL ID | CHEMBL1201109 |
ChEBI ID | 204734 |
PubChem CID | 5311066 |
DrugBank | DB01260 |
UNII ID | J280872D1O (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
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Safety
Black-box Warning
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Adverse Events
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15 adverse events reported
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