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Dexchlorpheniramine
Polaramine (dexchlorpheniramine) is a small molecule pharmaceutical. Dexchlorpheniramine was first approved as Polaramine on 1982-01-01. It is used to treat allergic conjunctivitis, allergic rhinitis perennial, allergic rhinitis seasonal, angioedema, and vasomotor rhinitis in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
respiratory tract diseasesD012140
otorhinolaryngologic diseasesD010038
eye diseasesD005128
cardiovascular diseasesD002318
skin and connective tissue diseasesD017437
immune system diseasesD007154
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
Brand Name
Status
Last Update
polmonANDA2020-11-09
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
allergic conjunctivitisEFO_0007141D003233H10.44
allergic rhinitis perennialEFO_1001417D012221J30.89
allergic rhinitis seasonalEFO_0003956D006255J30
angioedemaEFO_0005532D000799T78.3
vasomotor rhinitisEFO_0007533D012223J30.0
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
R: Respiratory system drugs
— R06: Antihistamines for systemic use
— R06A: Antihistamines for systemic use
— R06AB: Substituted alkylamines, systemic antihistamines
— R06AB02: Dexchlorpheniramine
— R06AB52: Dexchlorpheniramine, combinations
HCPCS
No data
Clinical
Indications Phases 4
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Indications Phases 3
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Indications Phases 2
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Indications Phases 1
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Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameDEXCHLORPHENIRAMINE
INNdexchlorpheniramine
Description
Dexchlorpheniramine is a chlorphenamine. It is an enantiomer of a levochlorpheniramine.
Classification
Small molecule
Drug class—
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
CN(C)CC[C@@H](c1ccc(Cl)cc1)c1ccccn1
Identifiers
PDB—
CAS-ID25523-97-1
RxCUI22697
ChEMBL IDCHEMBL1201353
ChEBI ID4464
PubChem CID33036
DrugBankDB13679
UNII ID3Q9Q0B929N (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Additional graphs summarizing 439 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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82 adverse events reported
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