Dexibuprofen
Dexibuprofen is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Clinical
Clinical Trials
632 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Pain | D010146 | EFO_0003843 | R52 | 12 | 12 | 25 | 27 | 13 | 88 |
Postoperative pain | D010149 | G89.18 | 4 | 8 | 13 | 22 | 12 | 58 | |
Healthy volunteers/patients | — | 40 | — | — | 3 | 2 | 45 | ||
Patent ductus arteriosus | D004374 | HP_0001643 | Q25.0 | 2 | 9 | 10 | 9 | 12 | 39 |
Fever | D005334 | HP_0001945 | R50.9 | 2 | — | 5 | 10 | 3 | 20 |
Low back pain | D017116 | HP_0003419 | M54.5 | — | 2 | 4 | 10 | 2 | 17 |
Acute pain | D059787 | R52 | 2 | 2 | 5 | 7 | 1 | 17 | |
Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | 3 | 3 | 6 | 2 | — | 14 |
Analgesia | D000698 | — | 2 | 6 | 6 | — | 13 | ||
Knee osteoarthritis | D020370 | EFO_0004616 | M17 | 3 | 2 | — | 3 | 3 | 10 |
Show 86 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Neoplasms | D009369 | C80 | — | 2 | 1 | — | 1 | 4 | |
Local anesthesia | D000772 | — | 2 | 1 | — | 1 | 3 | ||
Breast neoplasms | D001943 | EFO_0003869 | C50 | 1 | — | 1 | — | 1 | 3 |
Altitude sickness | D000532 | EFO_1000782 | T70.29 | 1 | — | 1 | — | 1 | 3 |
Impacted tooth | D014095 | HP_0011079 | K01.1 | — | 1 | 2 | — | 1 | 3 |
Sprains and strains | D013180 | — | — | 3 | — | — | 3 | ||
Pregnancy | D011247 | EFO_0002950 | Z33.1 | — | 1 | 1 | — | — | 2 |
Cachexia | D002100 | HP_0004326 | R64 | — | — | 1 | — | 1 | 2 |
Musculoskeletal pain | D059352 | — | 1 | 1 | — | — | 2 | ||
Ankle injuries | D016512 | S93.4 | — | — | 1 | — | 1 | 2 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Tuberculosis | D014376 | EFO_0000774 | A15-A19 | — | 2 | — | — | — | 2 |
Phimosis | D010688 | EFO_1001104 | N47.1 | 1 | 1 | — | — | — | 2 |
Paraphimosis | D010263 | EFO_1001086 | N47.2 | 1 | 1 | — | — | — | 2 |
Balanitis | D001446 | EFO_1000833 | N48.1 | 1 | 1 | — | — | — | 2 |
Retinopathy of prematurity | D012178 | EFO_1001158 | H35.1 | — | 1 | — | — | 1 | 2 |
Malaria | D008288 | EFO_0001068 | B54 | 1 | 2 | — | — | — | 2 |
Abdominal hernia | D046449 | K46 | — | 1 | — | — | 1 | 2 | |
Bronchopulmonary dysplasia | D001997 | P27.8 | — | 2 | — | — | — | 2 | |
Soft tissue injuries | D017695 | — | 1 | — | — | 1 | 2 | ||
Temporomandibular joint disorders | D013705 | M26.6 | 1 | 1 | — | — | 1 | 2 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Therapeutic equivalency | D013810 | 4 | — | — | — | — | 4 | ||
Pharmacokinetics | D010599 | 1 | — | — | — | 1 | 2 | ||
Staphylococcal infections | D013203 | A49.01 | 1 | — | — | — | — | 1 | |
Drug interactions | D004347 | 1 | — | — | — | — | 1 | ||
Pure autonomic failure | D054970 | 1 | — | — | — | — | 1 | ||
Orthostatic hypotension | D007024 | I95.1 | 1 | — | — | — | — | 1 | |
Hematologic neoplasms | D019337 | 1 | — | — | — | — | 1 | ||
Precursor cell lymphoblastic leukemia-lymphoma | D054198 | C91.0 | 1 | — | — | — | — | 1 | |
Bcr-abl positive chronic myelogenous leukemia | D015464 | EFO_0000340 | 1 | — | — | — | — | 1 | |
Hodgkin disease | D006689 | C81 | 1 | — | — | — | — | 1 |
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Cystic fibrosis | D003550 | EFO_0000390 | E84 | — | — | — | — | 3 | 3 |
Leg ulcer | D007871 | — | — | — | — | 2 | 2 | ||
Colonic neoplasms | D003110 | C18 | — | — | — | — | 1 | 1 | |
Arthritis | D001168 | EFO_0005856 | M05-M14 | — | — | — | — | 1 | 1 |
Urinary calculi | D014545 | N20.9 | — | — | — | — | 1 | 1 | |
Pediatric obesity | D063766 | — | — | — | — | 1 | 1 | ||
Appetitive behavior | D001070 | — | — | — | — | 1 | 1 | ||
Platelet aggregation | D010974 | GO_0070527 | — | — | — | — | 1 | 1 | |
Pneumonia | D011014 | EFO_0003106 | J18 | — | — | — | — | 1 | 1 |
Forearm injuries | D005543 | S59.91 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common name | DEXIBUPROFEN |
INN | dexibuprofen |
Description | Dexibuprofen is an ibuprofen. It has a role as a non-narcotic analgesic and a non-steroidal anti-inflammatory drug. It is an enantiomer of a levibuprofen. |
Classification | Small molecule |
Drug class | anti-inflammatory/analgesic agents (ibuprofen type) |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | CC(C)Cc1ccc([C@H](C)C(=O)O)cc1 |
Identifiers
PDB | — |
CAS-ID | 51146-56-6 |
RxCUI | — |
ChEMBL ID | CHEMBL175 |
ChEBI ID | 43415 |
PubChem CID | 39912 |
DrugBank | DB09213 |
UNII ID | 671DKG7P5S (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Financial
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 485 documents
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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77 adverse events reported
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