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Dicloxacillin
Dycill, Dynapen, Pathocil (dicloxacillin) is a small molecule pharmaceutical. Dicloxacillin was first approved as Dynapen on 1982-01-01. It is used to treat bacterial infections, bacterial pneumonia, cellulitis, osteomyelitis, and postoperative complications amongst others in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
musculoskeletal diseasesD009140
respiratory tract diseasesD012140
urogenital diseasesD000091642
skin and connective tissue diseasesD017437
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Dicloxacillin sodium
Tradename
Company
Number
Date
Products
DYNAPENBristol Myers SquibbN-050337 DISCN1982-01-01
1 products
PATHOCILWyethN-050011 DISCN1982-01-01
2 products, RLD
PATHOCILWyethN-050092 DISCN1982-01-01
1 products
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Labels
FDA
EMA
Brand Name
Status
Last Update
dicloxacillin sodiumANDA2022-09-26
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
bacterial infections—D001424A49
bacterial pneumoniaEFO_1001272D018410J15.9
cellulitisEFO_0003035D002481L03.90
osteomyelitisEFO_0003102D010019M86
postoperative complications—D011183—
soft tissue infections—D018461—
staphylococcal skin infectionsEFO_1001849D013207L00
urinary tract infectionsEFO_0003103D014552N39.0
wound infection—D014946—
Agency Specific
FDA
EMA
Expiration
Code
DICLOXACILLIN SODIUM, DICLOXACILLIN SODIUM, AUROBINDO PHARMA
2023-03-29CGT
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01C: Beta-lactam antibacterials, penicillins
— J01CF: Beta-lactamase resistant penicillins
— J01CF01: Dicloxacillin
HCPCS
No data
Clinical
Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameDICLOXACILLIN
INNdicloxacillin
Description
Dicloxacillin is a penicillin that is 6-aminopenicillanic acid in which one of the amino hydrogens is replaced by a 3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]formyl group. It has a role as an antibacterial drug. It is a penicillin and a dichlorobenzene. It is a conjugate acid of a dicloxacillin(1-).
Classification
Small molecule
Drug classpenicillins
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Cc1onc(-c2c(Cl)cccc2Cl)c1C(=O)N[C@@H]1C(=O)N2[C@@H](C(=O)O)C(C)(C)S[C@H]12
Identifiers
PDB—
CAS-ID3116-76-5
RxCUI3356
ChEMBL IDCHEMBL893
ChEBI ID4511
PubChem CID18381
DrugBankDB00485
UNII IDCOF19H7WBK (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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114 adverse events reported
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