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Dienestrol
Dv, Estraguard (dienestrol) is a small molecule pharmaceutical. Dienestrol was first approved as Dienestrol on 1982-01-01. It is used to treat atrophic vaginitis and vulvar lichen sclerosus in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
urogenital diseasesD000091642
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Dienestrol
Tradename
Company
Number
Date
Products
DIENESTROLJohnson & JohnsonN-006110 DISCN1982-01-01
1 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
atrophic vaginitisEFO_1001271D059268—
vulvar lichen sclerosus—D007724N90.4
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
G: Genito urinary system and sex hormones
— G03: Sex hormones and modulators of the genital system
— G03C: Estrogens, sex hormones and modulators of the genital system
— G03CB: Synthetic estrogens, plain
— G03CB01: Dienestrol
— G03CC: Estrogens, combinations with other drugs
— G03CC02: Dienestrol
HCPCS
No data
Clinical
Clinical Trials
1 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Cerebral hemorrhageD002543————11
Craniocerebral traumaD006259S00————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameDIENESTROL
INNdienestrol
Description
Dienestrol is an olefinic compound that is hexa-2,4-diene substituted by 4-hydroxyphenyl groups at positions 3 and 4 respectively. It has a role as a xenoestrogen. It is a member of phenols and an olefinic compound.
Classification
Small molecule
Drug classestrogens
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
C/C=C(C(=C/C)/c1ccc(O)cc1)\c1ccc(O)cc1
Identifiers
PDB—
CAS-ID13029-44-2
RxCUI—
ChEMBL IDCHEMBL1018
ChEBI ID—
PubChem CID667476
DrugBankDB00890
UNII IDRRW32X4U1F (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 167 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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19 adverse events reported
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