Skip to content
Dopamine
Intropin (dopamine) is a small molecule pharmaceutical. Dopamine was first approved as Dopamine hydrochloride on 1982-01-01. It is used to treat bradycardia, heart block, hypotension, kidney diseases, and low cardiac output amongst others in the USA. The pharmaceutical is active against D(2) dopamine receptor, D(4) dopamine receptor, D(1B) dopamine receptor, D(3) dopamine receptor, and D(1A) dopamine receptor. In addition, it is known to target glucose-dependent insulinotropic receptor, transient receptor potential cation channel subfamily M member 8, and transient receptor potential cation channel subfamily V member 1.
Download report
Favorite
Commercial
Therapeutic Areas
Therapeutic Area
MeSH
urogenital diseasesD000091642
cardiovascular diseasesD002318
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Dopamine hydrochloride
Tradename
Company
Number
Date
Products
DOPAMINE HYDROCHLORIDE IN DEXTROSE 5% IN PLASTIC CONTAINERBaxterN-019615 RX1987-03-27
4 products, RLD, RS
DOPAMINE HYDROCHLORIDEHospiraN-018132 RX1982-01-01
4 products, RLD, RS
DOPAMINE HYDROCHLORIDE IN DEXTROSE 5% IN PLASTIC CONTAINERHospiraN-018826 RX1983-09-30
3 products, RLD, RS
Show 11 discontinued
Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
bradycardiaHP_0001662D001919R00.1
heart block—D006327I45.89
hypotensionEFO_0005251D007022I95
kidney diseasesEFO_0003086D007674N08
low cardiac output—D002303—
shock—D012769R57.1
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
C: Cardiovascular system drugs
— C01: Cardiac therapy drugs
— C01C: Cardiac stimulants excl. cardiac glycosides
— C01CA: Adrenergic and dopaminergic cardiac stimulants
— C01CA04: Dopamine
N: Nervous system drugs
— N04: Anti-parkinson drugs
— N04B: Dopaminergic agents
— N04BC: Dopamine agonists
HCPCS
Code
Description
J1265
Injection, dopamine hcl, 40 mg
Clinical
Clinical Trials
8 clinical trials
View more details
Mock data
Subscribe for the real data
Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
VomitingD014839HP_0002013R11.1—11215
NauseaD009325HP_0002018R11.01——1—2
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeoplasmsD009369C80—11——2
FibromyalgiaD005356EFO_0005687M79.1——1——1
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Postoperative nausea and vomitingD020250EFO_0004888————11
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameDOPAMINE
INNdopamine
Description
Dopamine is catechol in which the hydrogen at position 4 is substituted by a 2-aminoethyl group. It has a role as a cardiotonic drug, a beta-adrenergic agonist, a dopaminergic agent, a sympathomimetic agent, a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a conjugate base of a dopaminium(1+).
Classification
Small molecule
Drug classdopaminergics (butopamine type)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
NCCc1ccc(O)c(O)c1
Identifiers
PDB—
CAS-ID51-61-6
RxCUI3628
ChEMBL IDCHEMBL59
ChEBI ID18243
PubChem CID681
DrugBankDB00988
UNII IDVTD58H1Z2X (ChemIDplus, GSRS)
Target
Agency Approved
DRD2
DRD2
DRD4
DRD4
DRD5
DRD5
DRD3
DRD3
DRD1
DRD1
Organism
Homo sapiens
Gene name
DRD2
Gene synonyms
NCBI Gene ID
1813
Protein name
D(2) dopamine receptor
Protein synonyms
Dopamine D2 receptor, seven transmembrane helix receptor
Uniprot ID
Q9UPA9
Mouse ortholog
Drd2 (13489)
D(2) dopamine receptor (Q0VGH9)
Alternate
GPR119
GPR119
TRPM8
TRPM8
TRPV1
TRPV1
Organism
Homo sapiens
Gene name
GPR119
Gene synonyms
NCBI Gene ID
139760
Protein name
glucose-dependent insulinotropic receptor
Protein synonyms
G-protein coupled receptor 119, G-protein coupled receptor 2
Uniprot ID
Q8TDV5
Mouse ortholog
Gpr119 (236781)
glucose-dependent insulinotropic receptor (Q7TQP3)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Additional graphs summarizing 240,379 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
90 adverse events reported
View more details