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Ensartinib
Ensartinib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target hepatocyte growth factor receptor and ALK tyrosine kinase receptor.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
25 clinical trials
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Mock data
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Non-small-cell lung carcinomaD0022897112—220
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Lung neoplasmsD008175C34.9022———4
NeoplasmsD009369C8032———3
Non-hodgkin lymphomaD008228C85.9—2———2
SarcomaD012509—2———2
NeuroblastomaD009447EFO_0000621—2———2
GliomaD005910EFO_0000520—2———2
OsteosarcomaD012516—2———2
Central nervous system neoplasmsD016543—2———2
MedulloblastomaD008527—2———2
Rhabdoid tumorD018335—2———2
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Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameENSARTINIB
INNensartinib
Description
Ensartinib is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target hepatocyte growth factor receptor and ALK tyrosine kinase receptor.
Classification
Small molecule
Drug classtyrosine kinase inhibitors
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
C[C@H]1CN(C(=O)c2ccc(NC(=O)c3cc(O[C@H](C)c4c(Cl)ccc(F)c4Cl)c(N)nn3)cc2)C[C@@H](C)N1
Identifiers
PDB—
CAS-ID1365267-27-1
RxCUI—
ChEMBL IDCHEMBL4113131
ChEBI ID—
PubChem CID—
DrugBank—
UNII IDSMA5ZS5B22 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
MET
MET
ALK
ALK
Organism
Homo sapiens
Gene name
MET
Gene synonyms
NCBI Gene ID
4233
Protein name
hepatocyte growth factor receptor
Protein synonyms
HGF receptor, HGF/SF receptor, Proto-oncogene c-Met, Scatter factor receptor, SF receptor, Tyrosine-protein kinase Met
Uniprot ID
Q9UPL8
Mouse ortholog
Met (17295)
hepatocyte growth factor receptor (P16056)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 328 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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