Etanidazole
Etanidazole is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Indications
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Agency Specific
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ATC Codes
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HCPCS
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Clinical
Clinical Trials
22 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Uterine cervical neoplasms | D002583 | 1 | 1 | — | — | 2 | 4 | ||
| Ovarian epithelial carcinoma | D000077216 | — | 1 | — | — | 2 | 3 | ||
| Non-small-cell lung carcinoma | D002289 | 1 | 1 | — | — | 1 | 3 | ||
| Head and neck neoplasms | D006258 | 2 | 1 | — | — | — | 3 | ||
| Squamous cell carcinoma of head and neck | D000077195 | — | 1 | — | — | — | 1 | ||
| Endometrial neoplasms | D016889 | EFO_0004230 | — | 1 | — | — | — | 1 | |
| Lung neoplasms | D008175 | C34.90 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Sarcoma | D012509 | 1 | — | — | — | 2 | 3 | ||
| Glioblastoma | D005909 | EFO_0000515 | 1 | — | — | — | 1 | 2 | |
| Glioma | D005910 | EFO_0000520 | 1 | — | — | — | 1 | 2 | |
| Gliosarcoma | D018316 | 1 | — | — | — | 1 | 2 | ||
| Ependymoma | D004806 | 1 | — | — | — | 1 | 2 | ||
| Astrocytoma | D001254 | EFO_0000271 | 1 | — | — | — | 1 | 2 | |
| Oligodendroglioma | D009837 | EFO_0000631 | 1 | — | — | — | 1 | 2 | |
| Subependymal glioma | D018315 | EFO_1001197 | 1 | — | — | — | 1 | 2 | |
| Neoplasms | D009369 | C80 | 2 | — | — | — | — | 2 | |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 2 | — | — | — | — | 2 |
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Fallopian tube neoplasms | D005185 | — | — | — | — | 2 | 2 | ||
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | — | — | — | — | 2 | 2 |
| Hypoxia | D000860 | R09.02 | — | — | — | — | 1 | 1 | |
| Peritoneal neoplasms | D010534 | — | — | — | — | 1 | 1 | ||
| Squamous cell neoplasms | D018307 | — | — | — | — | 1 | 1 | ||
| Squamous cell carcinoma | D002294 | — | — | — | — | 1 | 1 | ||
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | — | — | — | — | 1 | 1 |
| Stomach neoplasms | D013274 | EFO_0003897 | C16 | — | — | — | — | 1 | 1 |
| Gastrointestinal stromal tumors | D046152 | EFO_0000505 | C49.A | — | — | — | — | 1 | 1 |
| Colonic neoplasms | D003110 | C18 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | ETANIDAZOLE |
| INN | etanidazole |
| Description | Etanidazole is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of (2-nitro-1H-imidazol-1-yl)acetic acid with the amino group of ethanolamine. Used as a radiosensitising agent for hypoxic tumour cells. It has a role as an antineoplastic agent, a prodrug, an alkylating agent and a radiosensitizing agent. It is a member of imidazoles, a C-nitro compound and a monocarboxylic acid amide. It is functionally related to an ethanolamine. |
| Classification | Small molecule |
| Drug class | antiprotozoal substances (metronidazole type) |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | O=C(Cn1ccnc1[N+](=O)[O-])NCCO |
Identifiers
| PDB | — |
| CAS-ID | 22668-01-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL47405 |
| ChEBI ID | 75473 |
| PubChem CID | 3276 |
| DrugBank | DB12736 |
| UNII ID | 30DKA3Q1HL (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Financial
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Trends
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Additional graphs summarizing 281 documents
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
0 adverse events reported
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