Setogepram
Setogepram is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target G-protein coupled receptor 84 and free fatty acid receptor 1.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
9 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Alstrom syndrome | D056769 | Orphanet_64 | Q87.8 | — | 1 | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | 2 | — | — | — | 2 |
| Metabolic syndrome | D024821 | EFO_0000195 | E88.81 | — | 2 | — | — | — | 2 |
| Inflammation | D007249 | 1 | 1 | — | — | — | 2 | ||
| Cystic fibrosis | D003550 | EFO_0000390 | E84 | — | 1 | — | — | — | 1 |
| Idiopathic pulmonary fibrosis | D054990 | J84.112 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | 1 | — | — | — | — | 1 | ||
| Fibrosis | D005355 | 1 | — | — | — | — | 1 | ||
| Hyperammonemia | D022124 | HP_0001987 | E72.20 | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | SETOGEPRAM |
| INN | fezagepras |
| Description | Setogepram is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target G-protein coupled receptor 84 and free fatty acid receptor 1. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | CCCCCc1cccc(CC(=O)O)c1 |
Identifiers
| PDB | — |
| CAS-ID | 1002101-19-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297635 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 879OVM0Y1S (ChemIDplus, GSRS) |
Target
Agency Approved
No data
Alternate
GPR84
GPR84
FFAR1
FFAR1
Organism
Homo sapiens
Gene name
GPR84
Gene synonyms
EX33
NCBI Gene ID
Protein name
G-protein coupled receptor 84
Protein synonyms
inflammation-related G protein-coupled receptor EX33, Inflammation-related G-protein coupled receptor EX33
Uniprot ID
Mouse ortholog
Gpr84 (80910)
G-protein coupled receptor 84 (Q8CIM5)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 4 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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