Flupentixol
Flupentixol is a small molecule pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against D(2) dopamine receptor and D(1A) dopamine receptor. In addition, it is known to target D(3) dopamine receptor and D(1B) dopamine receptor.
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Clinical
Clinical Trials
14 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Schizophrenia | D012559 | EFO_0000692 | F20 | — | — | 1 | 2 | — | 3 |
| Depression | D003863 | F33.9 | — | — | 1 | 1 | — | 2 | |
| Dyspepsia | D004415 | EFO_0008533 | K30 | — | — | — | 1 | — | 1 |
| Compliance | D003187 | — | — | — | 1 | — | 1 | ||
| Metabolic syndrome | D024821 | EFO_0000195 | E88.81 | — | — | — | 1 | — | 1 |
| Therapeutics | D013812 | — | — | — | 1 | — | 1 | ||
| Central nervous system diseases | D002493 | HP_0002011 | G96.9 | — | — | — | 1 | — | 1 |
| Nervous system diseases | D009422 | G00-G99 | — | — | — | 1 | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Cocaine-related disorders | D019970 | F14 | 1 | 3 | — | — | — | 4 | |
| Substance-related disorders | D019966 | EFO_0003890 | F13 | — | 2 | — | — | — | 2 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Therapeutic equivalency | D013810 | 1 | — | — | — | — | 1 | ||
| Healthy volunteers/patients | — | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | FLUPENTIXOL |
| INN | flupentixol |
| Description | Cis-flupenthixol is a flupenthixol in which the double bond adopts a cis-configuration. It has a role as a dopaminergic antagonist. It is a conjugate base of a cis-flupenthixol(2+). |
| Classification | Small molecule |
| Drug class | Typical antipsychotic |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | OCCN1CCN(CC/C=C2/c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1 |
Identifiers
| PDB | — |
| CAS-ID | 53772-82-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL54661 |
| ChEBI ID | 10454 |
| PubChem CID | 5281881 |
| DrugBank | DB00875 |
| UNII ID | 21HMQ851IS (ChemIDplus, GSRS) |
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Additional graphs summarizing 982 documents
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Safety
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Adverse Events
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1,068 adverse events reported
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