Glembatumumab
Glembatumumab is an antibody pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
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HCPCS
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Clinical
Clinical Trials
11 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Triple negative breast neoplasms | D064726 | 2 | 2 | — | — | 1 | 4 | ||
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 2 | 3 | — | — | — | 3 |
| Melanoma | D008545 | 2 | 3 | — | — | — | 3 | ||
| Uveal neoplasms | D014604 | EFO_1001230 | 1 | 2 | — | — | — | 2 | |
| Squamous cell carcinoma of head and neck | D000077195 | 1 | 1 | — | — | — | 1 | ||
| Osteosarcoma | D012516 | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | GLEMBATUMUMAB |
| INN | glembatumumab |
| Description | Glembatumumab vedotin (also known as CDX-011 and CR011-vcMMAE) is an antibody-drug conjugate (ADC) that targets cancer cells expressing transmembrane glycoprotein NMB (GPNMB).
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| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 1020264-78-1 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108707 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | WEC7MEM1BR (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Financial
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Trends
PubMed Central
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Additional graphs summarizing 282 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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