D-glutamate
D-glutamate is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Abbreviated New Drug Application (ANDA)
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Clinical
Clinical Trials
31 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Heart transplantation | D016027 | EFO_0010673 | — | — | — | 1 | — | 1 | |
| Allergic conjunctivitis | D003233 | EFO_0007141 | H10.44 | — | — | — | 1 | — | 1 |
| Vertigo | D014717 | H81.39 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Coronary artery bypass | D001026 | EFO_0003776 | — | — | 2 | — | — | 2 | |
| Leukemia | D007938 | C95 | — | — | 1 | — | — | 1 | |
| Sarcoma | D012509 | — | — | 1 | — | — | 1 | ||
| Lymphoma | D008223 | C85.9 | — | — | 1 | — | — | 1 | |
| Kidney neoplasms | D007680 | EFO_0003865 | C64 | — | — | 1 | — | — | 1 |
| Peripheral nervous system diseases | D010523 | G64 | — | — | 1 | — | — | 1 | |
| Heart failure | D006333 | EFO_0003144 | I50 | — | — | 1 | — | — | 1 |
| Postoperative complications | D011183 | — | — | 1 | — | — | 1 | ||
| Myocardial infarction | D009203 | EFO_0000612 | I21 | — | — | 1 | — | — | 1 |
| Coronary artery disease | D003324 | I25.1 | — | — | 1 | — | — | 1 |
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 1 | 1 | — | — | — | 2 |
| Solitary pulmonary nodule | D003074 | R91.1 | — | 2 | — | — | — | 2 | |
| Lung neoplasms | D008175 | C34.90 | 1 | 2 | — | — | — | 2 | |
| Latent autoimmune diabetes in adults | D000071698 | — | 1 | — | — | — | 1 | ||
| Multiple pulmonary nodules | D055613 | — | 1 | — | — | — | 1 | ||
| Cervical intraepithelial neoplasia | D018290 | D06 | — | 1 | — | — | — | 1 | |
| Non-small-cell lung carcinoma | D002289 | 1 | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Prostatic neoplasms | D011471 | C61 | 1 | — | — | — | — | 1 | |
| Hiv infections | D015658 | EFO_0000764 | B20 | 1 | — | — | — | — | 1 |
| Colitis | D003092 | EFO_0003872 | K52.9 | 1 | — | — | — | — | 1 |
| Colorectal neoplasms | D015179 | 1 | — | — | — | — | 1 | ||
| Fallopian tube neoplasms | D005185 | 1 | — | — | — | — | 1 | ||
| Hepatocellular carcinoma | D006528 | C22.0 | 1 | — | — | — | — | 1 | |
| Cholangiocarcinoma | D018281 | C22.1 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Obesity | D009765 | EFO_0001073 | E66.9 | — | — | — | — | 1 | 1 |
| Exploratory behavior | D005106 | EFO_0004316 | — | — | — | — | 1 | 1 | |
| Epilepsy | D004827 | EFO_0000474 | G40.9 | — | — | — | — | 1 | 1 |
| Persian gulf syndrome | D018923 | EFO_0007430 | — | — | — | — | 1 | 1 | |
| Diet therapy | D004035 | — | — | — | — | 1 | 1 | ||
| Atherosclerosis | D050197 | EFO_0003914 | I25.1 | — | — | — | — | 1 | 1 |
| Multiple sclerosis | D009103 | EFO_0003885 | G35 | — | — | — | — | 1 | 1 |
| Autistic disorder | D001321 | EFO_0003758 | F84.0 | — | — | — | — | 1 | 1 |
| Gastroesophageal reflux | D005764 | EFO_0003948 | K21 | — | — | — | — | 1 | 1 |
| Irritable bowel syndrome | D043183 | EFO_0000555 | K58 | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | D-GLUTAMATE |
| INN | — |
| Description | D-glutamic acid is an optically active form of glutamic acid having D-configuration. It has a role as an Escherichia coli metabolite and a mouse metabolite. It is a D-alpha-amino acid and a glutamic acid. It is a conjugate acid of a D-glutamate(1-). It is an enantiomer of a L-glutamic acid. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | N[C@H](CCC(=O)O)C(=O)O |
Identifiers
| PDB | — |
| CAS-ID | 6893-26-1 |
| RxCUI | — |
| ChEMBL ID | CHEMBL76232 |
| ChEBI ID | 15966 |
| PubChem CID | 23327 |
| DrugBank | DB02517 |
| UNII ID | — |
Target
Agency Approved
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Alternate
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Variants
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Trends
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Safety
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