Gozetotide alf-18
Locametz (gozetotide alf-18) is a small molecule pharmaceutical. Gozetotide alf-18 was first approved as Locametz on 2022-12-09. It has been approved in Europe to treat radionuclide imaging.
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Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| diagnosis | D003933 |
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| locametz | New Drug Application | 2022-03-23 |
Indications
FDA
EMA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
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HCPCS
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Clinical
Clinical Trials
16 clinical trials
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Indications Phases 4
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Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Glioblastoma | D005909 | EFO_0000515 | — | — | — | — | 1 | 1 | |
| Gastrointestinal neoplasms | D005770 | C26.9 | — | — | — | — | 1 | 1 | |
| Papillary thyroid cancer | D000077273 | — | — | — | — | 1 | 1 | ||
| Medullary thyroid cancer | C536914 | — | — | — | — | 1 | 1 | ||
| Multiple myeloma | D009101 | C90.0 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | GOZETOTIDE ALF-18 |
| INN | — |
| Description | Locametz (gozetotide alf-18) is a small molecule pharmaceutical. Gozetotide alf-18 was first approved as Locametz on 2022-12-09. It has been approved in Europe to treat radionuclide imaging. |
| Classification | Small molecule |
| Drug class | peptides |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | O=C([O-])CN(CCN(CC(=O)[O-])Cc1cc(CCC(=O)NCCCCCC(=O)NCCCC[C@H](NC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O)ccc1O)Cc1cc(CCC(=O)O)ccc1O.[18F-].[Al+3] |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4650355 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | — |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
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Financial
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Trends
PubMed Central
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Additional graphs summarizing 17 documents
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
0 adverse events reported
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