Hydroxypropyl cellulose
Lacrisert (hydroxypropyl cellulose) is an unknown pharmaceutical. Hydroxypropyl cellulose was first approved as Lacrisert on 1982-01-01.
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
Lacrisert
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Hydroxypropyl cellulose
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| LACRISERT | Bausch Health Companies | N-018771 RX | 1982-01-01 | 1 products, RLD, RS |
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| lacrisert | New Drug Application | 2019-10-01 |
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
29 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Spontaneous abortion | D000022 | EFO_1001255 | O00.1 | — | — | — | 1 | — | 1 |
| Ovarian hyperstimulation syndrome | D016471 | — | — | — | 1 | — | 1 | ||
| Pre-eclampsia | D011225 | EFO_0000668 | O14 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Premature birth | D047928 | EFO_0003917 | O60 | — | 2 | 7 | — | 2 | 9 |
| Pregnancy | D011247 | EFO_0002950 | Z33.1 | 1 | 2 | 2 | — | — | 5 |
| Premature obstetric labor | D007752 | O60 | — | 1 | 1 | — | 1 | 3 | |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | — | 1 | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Premature rupture fetal membranes | D005322 | HP_0001788 | O42 | — | 1 | — | — | — | 1 |
| Pregnancy complications | D011248 | 1 | 1 | — | — | — | 1 |
Indications Phases 1
No data
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Placenta previa | D010923 | EFO_0007442 | O44 | — | — | — | — | 2 | 2 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | HYDROXYPROPYL CELLULOSE |
| INN | hyprolose |
| Description | Hydroxypropyl cellulose (HPC) is a derivative of cellulose with both water solubility and organic solubility. It is used as an excipient, and topical ophthalmic protectant and lubricant.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) | |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 9004-64-2 |
| RxCUI | 27291 |
| ChEMBL ID | CHEMBL1201471 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB00840 |
| UNII ID | 9XZ8H6N6OH (ChemIDplus, GSRS) |
Target
Agency Approved
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Alternate
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Variants
Clinical Variant
No data
Financial
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,951 documents
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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18,563 adverse events reported
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