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Idoxuridine
Dendrid, Herplex, Stoxil (idoxuridine) is a small molecule pharmaceutical. Idoxuridine was first approved as Dendrid on 1982-01-01. It is used to treat dendritic keratitis and virus diseases in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
eye diseasesD005128
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Idoxuridine
Tradename
Company
Number
Date
Products
DENDRIDAlcon ResearchN-014169 DISCN1982-01-01
1 products, RLD
HERPLEXAllerganN-013935 DISCN1982-01-01
1 products
STOXILGSKN-013934 DISCN1982-01-01
1 products
STOXILGSKN-015868 DISCN1982-01-01
1 products
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Labels
FDA
EMA
No data
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
dendritic keratitisEFO_1001883D007635—
virus diseases—D014777B34
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
D: Dermatologicals
— D06: Antibiotics and chemotherapeutics for dermatological use
— D06B: Chemotherapeutics for topical use
— D06BB: Antivirals, topical
— D06BB01: Idoxuridine
J: Antiinfectives for systemic use
— J05: Antivirals for systemic use
— J05A: Direct acting antivirals
— J05AB: Nucleosides and nucleotides excl. reverse transcriptase inhibitors
— J05AB02: Idoxuridine
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01A: Antiinfective ophthalmologics
— S01AD: Antivirals, ophthalmologic
— S01AD01: Idoxuridine
HCPCS
No data
Clinical
Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameIDOXURIDINE
INNidoxuridine
Description
5-iodo-2'-deoxyuridine is a pyrimidine 2'-deoxyribonucleoside compound having 5-iodouracil as the nucleobase; used as an antiviral agent. It has a role as an antiviral drug and a DNA synthesis inhibitor. It is a pyrimidine 2'-deoxyribonucleoside and an organoiodine compound.
Classification
Small molecule
Drug classantivirals; antineoplastics (uridine derivatives)
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
O=c1[nH]c(=O)n([C@H]2C[C@H](O)[C@@H](CO)O2)cc1I
Identifiers
PDB—
CAS-ID54-42-2
RxCUI5653
ChEMBL IDCHEMBL788
ChEBI ID147675
PubChem CID5905
DrugBankDB03778
UNII IDLGP81V5245 (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
No data
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
0 adverse events reported
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