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Ilacirnon
Ilacirnon is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target C-C chemokine receptor type 2.
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
No data
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
5 clinical trials
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Indications Phases 4
No data
Indications Phases 3
No data
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Type 2 diabetes mellitusD003924EFO_0001360E11—3———3
Focal segmental glomerulosclerosisD005923EFO_0004236—2———2
Diabetic nephropathiesD003928EFO_0000401—2———2
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameILACIRNON
INNilacirnon
Description
Ilacirnon is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target C-C chemokine receptor type 2.
Classification
Small molecule
Drug classChemokine receptor (CCR) antagonists, not antivirals
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)
Cc1cnc(C(=O)c2ncnc3[nH]ccc23)c(NS(=O)(=O)c2ccc(Cl)c(C(F)(F)F)c2)c1
Identifiers
PDB—
CAS-ID1100318-47-5
RxCUI—
ChEMBL IDCHEMBL2178573
ChEBI ID—
PubChem CID—
DrugBank—
UNII ID380F68J5PH (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
CCR2
CCR2
Organism
Homo sapiens
Gene name
CCR2
Gene synonyms
CMKBR2
NCBI Gene ID
729230
Protein name
C-C chemokine receptor type 2
Protein synonyms
CD192, chemokine (C-C motif) receptor 2, MCP-1 receptor, MCP-1-R, Monocyte chemoattractant protein 1 receptor, monocyte chemotactic protein 1 receptor
Uniprot ID
Q4VBL2
Mouse ortholog
Ccr2 (12772)
C-C chemokine receptor type 2 (Q61172)
Variants
Clinical Variant
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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11 adverse events reported
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